Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | NVP-TAE684 | 0.1 | uM | 1 | 5000.00 | 1498.27 | 3437.67 | 5071.08 | 0.6779 | 0.6032 |
| MCF7 | NVP-TAE684 | 0.31623 | uM | 1 | 5000.00 | 1498.27 | 2512.00 | 5071.08 | 0.4952 | 0.3410 |
| MCF7 | NVP-TAE684 | 1 | uM | 1 | 5000.00 | 1498.27 | 1725.67 | 5071.08 | 0.3402 | 0.0824 |
| MCF7 | NVP-TAE684 | 3.1623 | uM | 1 | 5000.00 | 1498.27 | 1278.33 | 5071.08 | 0.2522 | -0.0869 |
| MCF7 | NVP-TAE684 | 10 | uM | 1 | 5000.00 | 1498.27 | 1238.33 | 5071.08 | 0.2443 | -0.1027 |
| MCF7 | Palbociclib | 0.0033113 | uM | 1 | 5000.00 | 1498.27 | 4169.00 | 4705.25 | 0.8889 | 0.8627 |
| MCF7 | Palbociclib | 0.01 | uM | 1 | 5000.00 | 1498.27 | 4395.67 | 4705.25 | 0.9328 | 0.9112 |
| MCF7 | Palbociclib | 0.031623 | uM | 1 | 5000.00 | 1498.27 | 3503.00 | 4705.25 | 0.7424 | 0.6635 |
| MCF7 | Palbociclib | 0.1 | uM | 1 | 5000.00 | 1498.27 | 3751.67 | 4705.25 | 0.7956 | 0.7351 |
| MCF7 | Palbociclib | 0.31623 | uM | 1 | 5000.00 | 1498.27 | 2825.33 | 4705.25 | 0.6004 | 0.4660 |
| MCF7 | Palbociclib | 1 | uM | 1 | 5000.00 | 1498.27 | 2643.67 | 4705.25 | 0.5620 | 0.4100 |
| MCF7 | Palbociclib | 3.1623 | uM | 1 | 5000.00 | 1498.27 | 2689.67 | 4705.25 | 0.5719 | 0.4249 |
| MCF7 | Palbociclib | 10 | uM | 1 | 5000.00 | 1498.27 | 2379.00 | 4705.25 | 0.5040 | 0.3173 |
| MCF7 | Palbociclib | 19.9526 | uM | 1 | 5000.00 | 1498.27 | 2308.67 | 4705.25 | 0.4902 | 0.2967 |
| MCF 10A | Omipalisib | 0.0016596 | uM | 2 | 156.25 | 57.48 | 193.33 | 446.92 | 0.4563 | 0.5197 |
| MCF 10A | Omipalisib | 0.0033113 | uM | 2 | 156.25 | 57.48 | 159.67 | 446.92 | 0.3651 | 0.4157 |
| MCF 10A | Omipalisib | 0.01 | uM | 2 | 156.25 | 57.48 | 105.67 | 446.92 | 0.2291 | 0.1909 |
| MCF 10A | Omipalisib | 0.031623 | uM | 2 | 156.25 | 57.48 | 28.67 | 446.92 | 0.0647 | -0.2202 |
| MCF 10A | Omipalisib | 0.1 | uM | 2 | 156.25 | 57.48 | 18.33 | 446.92 | 0.0394 | -0.3560 |
| MCF 10A | Omipalisib | 0.31623 | uM | 2 | 156.25 | 57.48 | 9.67 | 446.92 | 0.0204 | -0.4813 |
| MCF 10A | Omipalisib | 1 | uM | 2 | 156.25 | 57.48 | 5.33 | 446.92 | 0.0124 | -0.5782 |
| MCF 10A | Omipalisib | 3.1623 | uM | 2 | 156.25 | 57.48 | 6.33 | 446.92 | 0.0147 | -0.5311 |
| MCF 10A | Omipalisib | 10 | uM | 2 | 156.25 | 57.48 | 14.00 | 446.92 | 0.0335 | -0.3884 |
| MCF 10A | Methotrexate | 0.0016596 | uM | 2 | 156.25 | 57.48 | 340.67 | 446.92 | 0.7473 | 0.7867 |
| MCF 10A | Methotrexate | 0.0033113 | uM | 2 | 156.25 | 57.48 | 531.67 | 446.92 | 1.1920 | 1.0840 |