Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Etoposide | 1 | uM | 2 | 1250.00 | 585.71 | 639.00 | 7602.33 | 0.0835 | 0.0184 |
| MCF 10A | Palbociclib | 19.9526 | uM | 6 | 625.00 | 231.54 | 495.33 | 5885.83 | 0.0838 | 0.1732 |
| MCF 10A | 17-AAG | 0.031623 | uM | 7 | 1250.00 | 252.38 | 921.67 | 10957.92 | 0.0838 | 0.2556 |
| MCF 10A | Erlotinib | 3.1623 | uM | 7 | 1250.00 | 252.38 | 919.33 | 10957.92 | 0.0841 | 0.2650 |
| MCF 10A | Palbociclib | 10 | uM | 2 | 625.00 | 277.50 | 281.67 | 3384.25 | 0.0845 | 0.0021 |
| MCF 10A | Omipalisib | 3.1623 | uM | 6 | 156.25 | 23.44 | 65.00 | 766.75 | 0.0845 | 0.2221 |
| MCF 10A | Etoposide | 19.9526 | uM | 5 | 1250.00 | 996.83 | 927.00 | 10901.42 | 0.0850 | -0.0213 |
| MCF 10A | Erlotinib | 3.1623 | uM | 7 | 312.50 | 61.21 | 144.67 | 1761.00 | 0.0851 | 0.1934 |
| MCF 10A | Taxol | 0.031623 | uM | 6 | 2500.00 | 1235.29 | 908.00 | 10609.25 | 0.0854 | -0.0984 |
| MCF 10A | Erlotinib | 3.1623 | uM | 8 | 625.00 | 218.83 | 334.00 | 3924.67 | 0.0855 | 0.1044 |
| MCF 10A | Etoposide | 3.1623 | uM | 5 | 1250.00 | 996.83 | 936.67 | 10901.42 | 0.0859 | -0.0179 |
| MCF 10A | Palbociclib | 10 | uM | 6 | 312.50 | 97.42 | 194.00 | 2267.17 | 0.0867 | 0.1638 |
| MCF 10A | Taxol | 0.1 | uM | 2 | 312.50 | 134.46 | 112.00 | 1303.25 | 0.0867 | -0.0633 |
| BT-20 | Omipalisib | 10 | uM | 4 | 2500.00 | 1354.79 | 379.33 | 4371.67 | 0.0867 | -0.5293 |
| MCF 10A | Taxol | 0.01 | uM | 6 | 156.25 | 23.44 | 66.67 | 766.75 | 0.0869 | 0.2274 |
| MCF 10A | Nilotinib | 19.9526 | uM | 2 | 1250.00 | 585.71 | 662.00 | 7602.33 | 0.0873 | 0.0332 |
| MCF 10A | Taxol | 1 | uM | 6 | 156.25 | 23.44 | 67.00 | 766.75 | 0.0878 | 0.2258 |
| MCF 10A | Taxol | 0.31623 | uM | 2 | 312.50 | 134.46 | 115.33 | 1303.25 | 0.0884 | -0.0507 |
| MCF 10A | Etoposide | 10 | uM | 6 | 156.25 | 23.44 | 76.67 | 869.00 | 0.0885 | 0.2545 |
| MCF 10A | Taxol | 0.01 | uM | 2 | 312.50 | 134.46 | 110.00 | 1303.25 | 0.0885 | -0.0640 |
| MCF 10A | Taxol | 0.01 | uM | 5 | 1250.00 | 996.83 | 997.00 | 11121.50 | 0.0896 | -0.0012 |
| MCF 10A | Omipalisib | 0.031623 | uM | 2 | 1250.00 | 585.71 | 614.33 | 6891.50 | 0.0896 | 0.0052 |
| MCF 10A | Palbociclib | 19.9526 | uM | 2 | 625.00 | 277.50 | 309.83 | 3384.25 | 0.0907 | 0.0110 |
| MCF 10A | Taxol | 1 | uM | 2 | 312.50 | 134.46 | 115.67 | 1303.25 | 0.0913 | -0.0446 |
| MCF 10A | Nilotinib | 19.9526 | uM | 5 | 625.00 | 399.25 | 819.67 | 8952.83 | 0.0916 | 0.1737 |