Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Palbociclib | 19.9526 | uM | 11 | 5000.00 | 2253.55 | 2791.33 | 5199.00 | 0.5876 | 0.2704 |
MCF7 | 17-AAG | 0.0016596 | uM | 10 | 156.25 | 46.73 | 146.00 | 104.00 | 1.4264 | 1.8002 |
MCF7 | 17-AAG | 0.0033113 | uM | 10 | 156.25 | 46.73 | 86.67 | 104.00 | 0.8591 | 0.7828 |
MCF7 | 17-AAG | 0.01 | uM | 10 | 156.25 | 46.73 | 87.67 | 104.00 | 0.8927 | 0.8600 |
MCF7 | 17-AAG | 0.031623 | uM | 10 | 156.25 | 46.73 | 71.33 | 104.00 | 0.6922 | 0.4495 |
MCF7 | 17-AAG | 0.1 | uM | 10 | 156.25 | 46.73 | 50.33 | 104.00 | 0.4779 | 0.0327 |
MCF7 | 17-AAG | 0.31623 | uM | 10 | 156.25 | 46.73 | 45.67 | 104.00 | 0.4531 | -0.0044 |
MCF7 | 17-AAG | 1 | uM | 10 | 156.25 | 46.73 | 46.33 | 104.00 | 0.4601 | 0.0095 |
MCF7 | 17-AAG | 3.1623 | uM | 10 | 156.25 | 46.73 | 33.67 | 104.00 | 0.3304 | -0.2501 |
MCF7 | 17-AAG | 10 | uM | 10 | 156.25 | 46.73 | 41.67 | 104.00 | 0.3904 | -0.1383 |
MCF7 | Erlotinib | 0.0033113 | uM | 10 | 156.25 | 46.73 | 134.00 | 104.00 | 1.2835 | 1.4887 |
MCF7 | Erlotinib | 0.01 | uM | 10 | 156.25 | 46.73 | 118.00 | 104.00 | 1.1699 | 1.3668 |
MCF7 | Erlotinib | 0.031623 | uM | 10 | 156.25 | 46.73 | 148.67 | 104.00 | 1.4584 | 1.8695 |
MCF7 | Erlotinib | 0.1 | uM | 10 | 156.25 | 46.73 | 129.33 | 104.00 | 1.2707 | 1.5334 |
MCF7 | Erlotinib | 0.31623 | uM | 10 | 156.25 | 46.73 | 147.33 | 104.00 | 1.4250 | 1.7652 |
MCF7 | Erlotinib | 1 | uM | 10 | 156.25 | 46.73 | 126.00 | 104.00 | 1.1787 | 1.2377 |
MCF7 | Erlotinib | 3.1623 | uM | 10 | 156.25 | 46.73 | 136.00 | 104.00 | 1.3465 | 1.6896 |
MCF7 | Erlotinib | 10 | uM | 10 | 156.25 | 46.73 | 153.00 | 104.00 | 1.4790 | 1.8586 |
MCF7 | Erlotinib | 19.9526 | uM | 10 | 156.25 | 46.73 | 273.00 | 104.00 | 2.7596 | 4.3451 |
MCF7 | Lapatinib | 0.0016596 | uM | 10 | 156.25 | 46.73 | 128.00 | 104.00 | 1.2594 | 1.5165 |
MCF7 | Lapatinib | 0.0033113 | uM | 10 | 156.25 | 46.73 | 212.33 | 104.00 | 2.0187 | 2.6910 |
MCF7 | Lapatinib | 0.01 | uM | 10 | 156.25 | 46.73 | 134.67 | 104.00 | 1.3104 | 1.5807 |
MCF7 | Lapatinib | 0.031623 | uM | 10 | 156.25 | 46.73 | 130.00 | 104.00 | 1.2861 | 1.5776 |
MCF7 | Lapatinib | 0.1 | uM | 10 | 156.25 | 46.73 | 136.33 | 104.00 | 1.3676 | 1.7537 |
MCF7 | Lapatinib | 0.31623 | uM | 10 | 156.25 | 46.73 | 143.67 | 104.00 | 1.3801 | 1.6629 |