Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Etoposide | 1 | uM | 6 | 312.50 | 97.42 | 125.00 | 2228.75 | 0.0561 | 0.0568 |
MCF 10A | PLX-4720 | 10 | uM | 6 | 312.50 | 97.42 | 1516.00 | 2228.75 | 0.6802 | 0.8364 |
MCF 10A | Etoposide | 10 | uM | 6 | 312.50 | 97.42 | 65.00 | 2228.75 | 0.0292 | -0.0857 |
MCF 10A | Nilotinib | 0.0033113 | uM | 6 | 312.50 | 97.42 | 3165.00 | 2228.75 | 1.4201 | 1.1615 |
MCF 10A | PLX-4720 | 0.01 | uM | 6 | 312.50 | 97.42 | 2553.00 | 2228.75 | 1.1455 | 1.0611 |
MCF 10A | 0 | uM | 6 | 312.50 | 97.42 | 1765.00 | 2228.75 | 0.7919 | 0.8993 | |
MCF 10A | 0 | uM | 6 | 312.50 | 97.42 | 2171.00 | 2228.75 | 0.9741 | 0.9884 | |
MCF 10A | 0 | uM | 6 | 625.00 | 231.54 | 6578.00 | 6173.50 | 1.0655 | 1.0270 | |
MCF 10A | 0 | uM | 6 | 625.00 | 231.54 | 6373.00 | 6173.50 | 1.0323 | 1.0135 | |
MCF 10A | Etoposide | 19.9526 | uM | 6 | 625.00 | 231.54 | 293.00 | 6173.50 | 0.0475 | 0.0510 |
MCF 10A | 0 | uM | 6 | 625.00 | 231.54 | 6343.00 | 6173.50 | 1.0275 | 1.0115 | |
MCF 10A | Nilotinib | 0.1 | uM | 6 | 625.00 | 231.54 | 6879.00 | 6173.50 | 1.1143 | 1.0462 |
MCF 10A | PLX-4720 | 0.31623 | uM | 6 | 625.00 | 231.54 | 5853.00 | 6173.50 | 0.9481 | 0.9776 |
MCF 10A | Nilotinib | 10 | uM | 6 | 625.00 | 231.54 | 1431.00 | 6173.50 | 0.2318 | 0.4689 |
MCF 10A | NVP-TAE684 | 3.1623 | uM | 6 | 625.00 | 231.54 | 665.00 | 6173.50 | 0.1077 | 0.2495 |
MCF 10A | NVP-TAE684 | 10 | uM | 6 | 625.00 | 231.54 | 317.00 | 6173.50 | 0.0513 | 0.0686 |
MCF 10A | PLX-4720 | 3.1623 | uM | 6 | 625.00 | 231.54 | 5673.00 | 6173.50 | 0.9189 | 0.9646 |
MCF 10A | PLX-4720 | 1 | uM | 6 | 625.00 | 231.54 | 6068.00 | 6173.50 | 0.9829 | 0.9927 |
MCF 10A | Nilotinib | 19.9526 | uM | 6 | 625.00 | 231.54 | 513.00 | 6173.50 | 0.0831 | 0.1829 |
MCF 10A | Nilotinib | 1 | uM | 6 | 625.00 | 231.54 | 6544.00 | 6173.50 | 1.0600 | 1.0248 |
MCF 10A | 0 | uM | 6 | 625.00 | 231.54 | 6618.00 | 6173.50 | 1.0720 | 1.0296 | |
MCF 10A | NVP-TAE684 | 1 | uM | 6 | 625.00 | 231.54 | 1227.00 | 6173.50 | 0.1988 | 0.4220 |
MCF 10A | Nilotinib | 0.031623 | uM | 6 | 625.00 | 231.54 | 5674.00 | 6173.50 | 0.9191 | 0.9647 |
MCF 10A | PLX-4720 | 0.0033113 | uM | 6 | 625.00 | 231.54 | 6366.00 | 6173.50 | 1.0312 | 1.0130 |
MCF 10A | Etoposide | 3.1623 | uM | 6 | 625.00 | 231.54 | 224.00 | 6173.50 | 0.0363 | -0.0070 |