LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TGX221 | 0.12 | uM | LJP5 | 0.8300 | 0.0433 | 0.8162 | 0.0477 |
| MDA-MB-231 | TGX221 | 0.37 | uM | LJP5 | 0.8388 | 0.0450 | 0.8260 | 0.0496 |
| MDA-MB-231 | TGX221 | 1.11 | uM | LJP5 | 0.8759 | 0.0235 | 0.8677 | 0.0240 |
| MDA-MB-231 | TGX221 | 3.33 | uM | LJP5 | 0.7266 | 0.0960 | 0.6911 | 0.1111 |
| MDA-MB-231 | TGX221 | 10 | uM | LJP5 | 0.8760 | 0.0162 | 0.8682 | 0.0174 |
| MDA-MB-231 | GSK1059615 | 0.04 | uM | LJP5 | 1.0517 | 0.0353 | 1.0513 | 0.0347 |
| MDA-MB-231 | GSK1059615 | 0.04 | uM | LJP6 | 1.0138 | 0.0593 | 1.0073 | 0.0639 |
| MDA-MB-231 | GSK1059615 | 0.12 | uM | LJP5 | 1.0117 | 0.0366 | 1.0110 | 0.0367 |
| MDA-MB-231 | GSK1059615 | 0.12 | uM | LJP6 | 0.9763 | 0.0209 | 0.9734 | 0.0235 |
| MDA-MB-231 | GSK1059615 | 0.37 | uM | LJP5 | 0.9154 | 0.0201 | 0.9105 | 0.0224 |
| MDA-MB-231 | GSK1059615 | 0.37 | uM | LJP6 | 0.9188 | 0.0361 | 0.9128 | 0.0384 |
| MDA-MB-231 | GSK1059615 | 1.11 | uM | LJP5 | 0.5750 | 0.0680 | 0.4990 | 0.0898 |
| MDA-MB-231 | GSK1059615 | 1.11 | uM | LJP6 | 0.6093 | 0.1021 | 0.5268 | 0.1403 |
| MDA-MB-231 | GSK1059615 | 3.33 | uM | LJP5 | 0.2819 | 0.0477 | 0.0354 | 0.0886 |
| MDA-MB-231 | GSK1059615 | 3.33 | uM | LJP6 | 0.4100 | 0.1127 | 0.2274 | 0.1829 |
| MDA-MB-231 | GSK1059615 | 10 | uM | LJP5 | 0.2380 | 0.0984 | -0.0862 | 0.1980 |
| MDA-MB-231 | GSK1059615 | 10 | uM | LJP6 | 0.2647 | 0.0769 | -0.0227 | 0.1467 |
| MDA-MB-231 | Brivanib | 0.04 | uM | LJP5 | 0.9105 | 0.0604 | 0.9023 | 0.0645 |
| MDA-MB-231 | Brivanib | 0.12 | uM | LJP5 | 0.8989 | 0.0436 | 0.8920 | 0.0466 |
| MDA-MB-231 | Brivanib | 0.37 | uM | LJP5 | 0.9157 | 0.0338 | 0.9096 | 0.0361 |
| MDA-MB-231 | Brivanib | 1.11 | uM | LJP5 | 0.9284 | 0.0339 | 0.9232 | 0.0358 |
| MDA-MB-231 | Brivanib | 3.33 | uM | LJP5 | 0.9035 | 0.0541 | 0.8951 | 0.0587 |
| MDA-MB-231 | Brivanib | 10 | uM | LJP5 | 0.7034 | 0.0447 | 0.6670 | 0.0544 |
| MDA-MB-231 | CHIR-99021 | 0.04 | uM | LJP6 | 0.9019 | 0.0226 | 0.8955 | 0.0234 |
| MDA-MB-231 | CHIR-99021 | 0.12 | uM | LJP6 | 0.8359 | 0.0241 | 0.8226 | 0.0223 |