LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GSK 690693 | 10 | uM | LJP5 | 0.7724 | 0.0329 | 0.6576 | 0.0374 |
| SK-BR-3 | SNS-032 | 0.04 | uM | LJP6 | 0.6671 | 0.0605 | 0.4637 | 0.1063 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 0.2915 | 0.0089 | -0.2228 | 0.0883 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 0.2480 | 0.0109 | -0.3120 | 0.0993 |
| SK-BR-3 | SNS-032 | 1.11 | uM | LJP6 | 0.2386 | 0.0104 | -0.3316 | 0.0961 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 0.2331 | 0.0201 | -0.3432 | 0.1191 |
| SK-BR-3 | SNS-032 | 10 | uM | LJP6 | 0.2218 | 0.0210 | -0.3672 | 0.1207 |
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 0.3350 | 0.0271 | -0.1373 | 0.1184 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 0.3385 | 0.0154 | -0.1295 | 0.0961 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 0.3447 | 0.0193 | -0.1174 | 0.0945 |
| SK-BR-3 | Afatinib | 1.11 | uM | LJP6 | 0.3710 | 0.0264 | -0.0678 | 0.1137 |
| SK-BR-3 | Afatinib | 3.33 | uM | LJP6 | 0.3790 | 0.0148 | -0.0514 | 0.0865 |
| SK-BR-3 | Afatinib | 10 | uM | LJP6 | 0.3168 | 0.0127 | -0.1713 | 0.0647 |
| SK-BR-3 | GSK1904529A | 0.04 | uM | LJP6 | 0.8072 | 0.0377 | 0.7014 | 0.0542 |
| SK-BR-3 | GSK1904529A | 0.12 | uM | LJP6 | 0.8977 | 0.0164 | 0.8413 | 0.0260 |
| SK-BR-3 | GSK1904529A | 0.37 | uM | LJP6 | 0.9856 | 0.0084 | 0.9801 | 0.0113 |
| SK-BR-3 | GSK1904529A | 1.11 | uM | LJP6 | 0.9878 | 0.0198 | 0.9855 | 0.0326 |
| SK-BR-3 | GSK1904529A | 3.33 | uM | LJP6 | 1.0221 | 0.0058 | 1.0358 | 0.0131 |
| SK-BR-3 | GSK1904529A | 10 | uM | LJP6 | 1.0310 | 0.0070 | 1.0494 | 0.0157 |
| SK-BR-3 | Linsitinib | 0.04 | uM | LJP5 | 0.7824 | 0.0631 | 0.6568 | 0.1107 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 0.8478 | 0.0387 | 0.7652 | 0.0648 |
| SK-BR-3 | Linsitinib | 0.37 | uM | LJP5 | 0.8693 | 0.0266 | 0.8059 | 0.0385 |
| SK-BR-3 | Linsitinib | 1.11 | uM | LJP5 | 0.8267 | 0.0281 | 0.7392 | 0.0416 |
| SK-BR-3 | Linsitinib | 3.33 | uM | LJP5 | 0.7895 | 0.0180 | 0.6784 | 0.0369 |
| SK-BR-3 | Linsitinib | 10 | uM | LJP5 | 0.7008 | 0.0216 | 0.5379 | 0.0488 |