LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Dasatinib | 0.04 | uM | LJP6 | 0.9804 | 0.0345 | 0.9777 | 0.0464 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP5 | 1.0003 | 0.0309 | 0.9927 | 0.0461 |
| SK-BR-3 | Dasatinib | 0.12 | uM | LJP6 | 0.9252 | 0.0019 | 0.8818 | 0.0111 |
| SK-BR-3 | Dasatinib | 0.37 | uM | LJP5 | 0.9775 | 0.0189 | 0.9626 | 0.0281 |
| SK-BR-3 | Dasatinib | 0.37 | uM | LJP6 | 0.9500 | 0.0244 | 0.9219 | 0.0400 |
| SK-BR-3 | Dasatinib | 1.11 | uM | LJP5 | 0.8493 | 0.0282 | 0.7719 | 0.0480 |
| SK-BR-3 | Dasatinib | 1.11 | uM | LJP6 | 0.8461 | 0.0247 | 0.7610 | 0.0336 |
| SK-BR-3 | Dasatinib | 3.33 | uM | LJP5 | 0.6679 | 0.0534 | 0.4838 | 0.0914 |
| SK-BR-3 | Dasatinib | 3.33 | uM | LJP6 | 0.5789 | 0.0197 | 0.3113 | 0.0634 |
| SK-BR-3 | Dasatinib | 10 | uM | LJP5 | 0.3938 | 0.0357 | 0.0068 | 0.0818 |
| SK-BR-3 | Dasatinib | 10 | uM | LJP6 | 0.2358 | 0.0100 | -0.3392 | 0.0558 |
| SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 0.3153 | 0.0018 | -0.1428 | 0.0652 |
| SK-BR-3 | Tozasertib | 0.12 | uM | LJP5 | 0.3282 | 0.0099 | -0.1167 | 0.0441 |
| SK-BR-3 | Tozasertib | 0.37 | uM | LJP5 | 0.3383 | 0.0054 | -0.0975 | 0.0616 |
| SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 0.3462 | 0.0021 | -0.0820 | 0.0584 |
| SK-BR-3 | Tozasertib | 3.33 | uM | LJP5 | 0.3411 | 0.0018 | -0.0918 | 0.0596 |
| SK-BR-3 | Tozasertib | 10 | uM | LJP5 | 0.3660 | 0.0073 | -0.0440 | 0.0590 |
| SK-BR-3 | Imatinib | 0.04 | uM | LJP6 | 1.0325 | 0.0166 | 1.0459 | 0.0228 |
| SK-BR-3 | Imatinib | 0.12 | uM | LJP6 | 1.0541 | 0.0225 | 1.0747 | 0.0260 |
| SK-BR-3 | Imatinib | 0.37 | uM | LJP6 | 1.0318 | 0.0261 | 1.0379 | 0.0353 |
| SK-BR-3 | Imatinib | 1.11 | uM | LJP6 | 1.0555 | 0.0235 | 1.0785 | 0.0264 |
| SK-BR-3 | Imatinib | 3.33 | uM | LJP6 | 1.0764 | 0.0254 | 1.1129 | 0.0380 |
| SK-BR-3 | Imatinib | 10 | uM | LJP6 | 0.9983 | 0.0148 | 0.9912 | 0.0249 |
| SK-BR-3 | NVP-TAE684 | 0.04 | uM | LJP6 | 1.0499 | 0.0150 | 1.0805 | 0.0270 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 0.8720 | 0.0701 | 0.7815 | 0.1151 |