LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | GDC-0980 | 0.37 | uM | LJP5 | 0.2177 | 0.0846 | 0.2578 | 0.0726 |
| MCF 10A | GDC-0980 | 1.11 | uM | LJP5 | 0.1408 | 0.0480 | 0.1075 | 0.0311 |
| MCF 10A | GDC-0980 | 3.33 | uM | LJP5 | 0.1309 | 0.0457 | 0.0839 | 0.0277 |
| MCF 10A | GDC-0980 | 10 | uM | LJP5 | 0.1123 | 0.0406 | 0.0356 | 0.0260 |
| MCF 10A | Mitoxantrone | 0.04 | uM | LJP5 | 0.2015 | 0.0556 | 0.2408 | 0.0325 |
| MCF 10A | Mitoxantrone | 0.04 | uM | LJP6 | 0.1877 | 0.0573 | 0.2148 | 0.0379 |
| MCF 10A | Mitoxantrone | 0.12 | uM | LJP5 | 0.1051 | 0.0256 | 0.0253 | 0.0159 |
| MCF 10A | Mitoxantrone | 0.12 | uM | LJP6 | 0.1014 | 0.0223 | 0.0222 | 0.0262 |
| MCF 10A | Mitoxantrone | 0.37 | uM | LJP5 | 0.0976 | 0.0269 | 0.0016 | 0.0093 |
| MCF 10A | Mitoxantrone | 0.37 | uM | LJP6 | 0.0919 | 0.0229 | -0.0097 | 0.0199 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 0.0832 | 0.0262 | -0.0503 | 0.0129 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 0.0812 | 0.0230 | -0.0482 | 0.0133 |
| MCF 10A | Mitoxantrone | 3.33 | uM | LJP5 | 0.0473 | 0.0113 | -0.1875 | 0.0577 |
| MCF 10A | Mitoxantrone | 3.33 | uM | LJP6 | 0.0461 | 0.0052 | -0.1840 | 0.0735 |
| MCF 10A | Mitoxantrone | 10 | uM | LJP5 | 0.0589 | 0.0155 | -0.1341 | 0.0399 |
| MCF 10A | Mitoxantrone | 10 | uM | LJP6 | 0.0527 | 0.0052 | -0.1501 | 0.0738 |
| MCF 10A | Radicicol | 0.04 | uM | LJP5 | 0.8158 | 0.0885 | 0.8905 | 0.0442 |
| MCF 10A | Radicicol | 0.04 | uM | LJP6 | 0.8049 | 0.0999 | 0.8819 | 0.0524 |
| MCF 10A | Radicicol | 0.12 | uM | LJP5 | 0.4940 | 0.1634 | 0.6033 | 0.1401 |
| MCF 10A | Radicicol | 0.12 | uM | LJP6 | 0.4780 | 0.1509 | 0.5930 | 0.1266 |
| MCF 10A | Radicicol | 0.37 | uM | LJP5 | 0.2529 | 0.0957 | 0.3046 | 0.1015 |
| MCF 10A | Radicicol | 0.37 | uM | LJP6 | 0.2410 | 0.0856 | 0.2941 | 0.0877 |
| MCF 10A | Radicicol | 1.11 | uM | LJP5 | 0.1376 | 0.0416 | 0.1044 | 0.0147 |
| MCF 10A | Radicicol | 1.11 | uM | LJP6 | 0.1350 | 0.0406 | 0.1028 | 0.0129 |
| MCF 10A | Radicicol | 3.33 | uM | LJP5 | 0.0903 | 0.0235 | -0.0204 | 0.0357 |