LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | Fedratinib | 1.11 | uM | LJP5 | 0.7967 | 0.0481 | 0.8757 | 0.0235 |
| MCF 10A | Fedratinib | 3.33 | uM | LJP5 | 0.3986 | 0.1362 | 0.5119 | 0.1095 |
| MCF 10A | Fedratinib | 10 | uM | LJP5 | 0.1185 | 0.0404 | 0.0536 | 0.0195 |
| MCF 10A | Trametinib | 0.04 | uM | LJP5 | 0.1612 | 0.0530 | 0.1523 | 0.0437 |
| MCF 10A | Trametinib | 0.12 | uM | LJP5 | 0.1720 | 0.0558 | 0.1778 | 0.0390 |
| MCF 10A | Trametinib | 0.37 | uM | LJP5 | 0.1754 | 0.0587 | 0.1818 | 0.0479 |
| MCF 10A | Trametinib | 1.11 | uM | LJP5 | 0.1842 | 0.0603 | 0.2022 | 0.0413 |
| MCF 10A | Trametinib | 3.33 | uM | LJP5 | 0.1845 | 0.0561 | 0.2058 | 0.0337 |
| MCF 10A | Trametinib | 10 | uM | LJP5 | 0.1967 | 0.0592 | 0.2307 | 0.0336 |
| MCF 10A | Omipalisib | 0.04 | uM | LJP6 | 0.1205 | 0.0400 | 0.0661 | 0.0275 |
| MCF 10A | Omipalisib | 0.12 | uM | LJP6 | 0.1005 | 0.0322 | 0.0112 | 0.0229 |
| MCF 10A | Omipalisib | 0.37 | uM | LJP6 | 0.0965 | 0.0304 | -0.0009 | 0.0096 |
| MCF 10A | Omipalisib | 1.11 | uM | LJP6 | 0.0931 | 0.0277 | -0.0097 | 0.0119 |
| MCF 10A | Omipalisib | 3.33 | uM | LJP6 | 0.0817 | 0.0273 | -0.0512 | 0.0089 |
| MCF 10A | Omipalisib | 10 | uM | LJP6 | 0.0626 | 0.0131 | -0.1123 | 0.0441 |
| MCF 10A | Buparlisib | 0.04 | uM | LJP5 | 0.9980 | 0.0141 | 1.0000 | 0.0071 |
| MCF 10A | Buparlisib | 0.12 | uM | LJP5 | 0.9184 | 0.0537 | 0.9560 | 0.0253 |
| MCF 10A | Buparlisib | 0.37 | uM | LJP5 | 0.7692 | 0.1168 | 0.8569 | 0.0647 |
| MCF 10A | Buparlisib | 1.11 | uM | LJP5 | 0.3904 | 0.1339 | 0.4868 | 0.1319 |
| MCF 10A | Buparlisib | 3.33 | uM | LJP5 | 0.1102 | 0.0376 | 0.0221 | 0.0512 |
| MCF 10A | Buparlisib | 10 | uM | LJP5 | 0.0477 | 0.0079 | -0.1811 | 0.0664 |
| MCF 10A | XL147 | 0.04 | uM | LJP5 | 1.0241 | 0.0040 | 1.0136 | 0.0007 |
| MCF 10A | XL147 | 0.12 | uM | LJP5 | 0.9698 | 0.0079 | 0.9815 | 0.0051 |
| MCF 10A | XL147 | 0.37 | uM | LJP5 | 0.9339 | 0.0183 | 0.9590 | 0.0123 |
| MCF 10A | XL147 | 1.11 | uM | LJP5 | 0.8955 | 0.0304 | 0.9343 | 0.0207 |