LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 0.9838 | 0.0436 | 0.9926 | 0.0280 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 0.9609 | 0.0434 | 0.9778 | 0.0270 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 0.9510 | 0.0327 | 0.9702 | 0.0196 |
| MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 0.9198 | 0.0346 | 0.9495 | 0.0217 |
| MCF 10A | Sorafenib | 10 | uM | LJP6 | 0.5222 | 0.0548 | 0.6497 | 0.0598 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 1.0307 | 0.0107 | 1.0175 | 0.0058 |
| MCF 10A | CP466722 | 0.12 | uM | LJP5 | 1.0267 | 0.0172 | 1.0141 | 0.0078 |
| MCF 10A | CP466722 | 0.37 | uM | LJP5 | 1.0143 | 0.0118 | 1.0075 | 0.0057 |
| MCF 10A | CP466722 | 1.11 | uM | LJP5 | 0.9876 | 0.0108 | 0.9939 | 0.0066 |
| MCF 10A | CP466722 | 3.33 | uM | LJP5 | 0.9488 | 0.0219 | 0.9723 | 0.0106 |
| MCF 10A | CP466722 | 10 | uM | LJP5 | 0.6182 | 0.2098 | 0.7289 | 0.1498 |
| MCF 10A | CP724714 | 0.04 | uM | LJP5 | 1.0194 | 0.0045 | 1.0105 | 0.0021 |
| MCF 10A | CP724714 | 0.12 | uM | LJP5 | 0.9949 | 0.0047 | 0.9964 | 0.0034 |
| MCF 10A | CP724714 | 0.37 | uM | LJP5 | 0.9833 | 0.0108 | 0.9890 | 0.0081 |
| MCF 10A | CP724714 | 1.11 | uM | LJP5 | 0.9740 | 0.0067 | 0.9839 | 0.0058 |
| MCF 10A | CP724714 | 3.33 | uM | LJP5 | 0.9742 | 0.0018 | 0.9849 | 0.0009 |
| MCF 10A | CP724714 | 10 | uM | LJP5 | 0.8963 | 0.0152 | 0.9384 | 0.0017 |
| MCF 10A | Alvocidib | 0.04 | uM | LJP6 | 0.2011 | 0.1104 | 0.1970 | 0.1545 |
| MCF 10A | Alvocidib | 0.12 | uM | LJP6 | 0.0436 | 0.0072 | -0.1996 | 0.0933 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 0.0295 | 0.0072 | -0.2881 | 0.1328 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 0.0307 | 0.0077 | -0.2813 | 0.1364 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 0.0310 | 0.0088 | -0.2810 | 0.1427 |
| MCF 10A | Alvocidib | 10 | uM | LJP6 | 0.0327 | 0.0062 | -0.2631 | 0.1264 |
| MCF 10A | GW843682X | 0.04 | uM | LJP6 | 0.9264 | 0.0340 | 0.9601 | 0.0154 |
| MCF 10A | GW843682X | 0.12 | uM | LJP6 | 0.7097 | 0.0855 | 0.8166 | 0.0477 |