LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
Hs 578T Ruxolitinib
10
uM
LJP5
 0.7027 0.0228 0.6934 0.0176
Hs 578T Momelotinib
0.04
uM
LJP5
 0.9311 0.0118 0.9312 0.0179
Hs 578T Momelotinib
0.12
uM
LJP5
 0.8482 0.0155 0.8507 0.0129
Hs 578T Momelotinib
0.37
uM
LJP5
 0.7637 0.0254 0.7623 0.0136
Hs 578T Momelotinib
1.11
uM
LJP5
 0.6524 0.0502 0.6385 0.0249
Hs 578T Momelotinib
3.33
uM
LJP5
 0.5041 0.0855 0.4469 0.0719
Hs 578T Momelotinib
10
uM
LJP5
 0.2615 0.0758 0.0460 0.0816
Hs 578T Fedratinib
0.04
uM
LJP5
 1.0102 0.0112 1.0115 0.0108
Hs 578T Fedratinib
0.12
uM
LJP5
 0.9835 0.0144 0.9863 0.0112
Hs 578T Fedratinib
0.37
uM
LJP5
 0.8801 0.0302 0.8866 0.0175
Hs 578T Fedratinib
1.11
uM
LJP5
 0.6653 0.0615 0.6552 0.0383
Hs 578T Fedratinib
3.33
uM
LJP5
 0.3765 0.0561 0.2581 0.0607
Hs 578T Fedratinib
10
uM
LJP5
 0.1605 0.0621 -0.1836 0.0992
Hs 578T Trametinib
0.04
uM
LJP5
 0.3771 0.0549 0.2608 0.0286
Hs 578T Trametinib
0.12
uM
LJP5
 0.3425 0.0601 0.2026 0.0412
Hs 578T Trametinib
0.37
uM
LJP5
 0.3384 0.0671 0.1942 0.0526
Hs 578T Trametinib
1.11
uM
LJP5
 0.3331 0.0633 0.1858 0.0511
Hs 578T Trametinib
3.33
uM
LJP5
 0.3289 0.0604 0.1791 0.0431
Hs 578T Trametinib
10
uM
LJP5
 0.3404 0.0651 0.1983 0.0528
Hs 578T Omipalisib
0.04
uM
LJP6
 0.3552 0.0414 0.2164 0.0426
Hs 578T Omipalisib
0.12
uM
LJP6
 0.2923 0.0547 0.1030 0.0697
Hs 578T Omipalisib
0.37
uM
LJP6
 0.2395 0.0602 -0.0024 0.0755
Hs 578T Omipalisib
1.11
uM
LJP6
 0.2005 0.0561 -0.0877 0.0751
Hs 578T Omipalisib
3.33
uM
LJP6
 0.1798 0.0565 -0.1384 0.0804
Hs 578T Omipalisib
10
uM
LJP6
 0.1592 0.0547 -0.1927 0.0795