LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
BT-20 Canertinib
10
uM
LJP6
 0.2526 0.0395 -0.1295 0.0562
BT-20 NVP-AEW541
0.04
uM
LJP5
 1.0205 0.0125 1.0237 0.0145
BT-20 NVP-AEW541
0.12
uM
LJP5
 1.0217 0.0104 1.0245 0.0117
BT-20 NVP-AEW541
0.37
uM
LJP5
 1.0274 0.0125 1.0324 0.0152
BT-20 NVP-AEW541
1.11
uM
LJP5
 1.0036 0.0179 1.0049 0.0209
BT-20 NVP-AEW541
3.33
uM
LJP5
 1.0239 0.0105 1.0268 0.0120
BT-20 NVP-AEW541
10
uM
LJP5
 0.8828 0.0549 0.8594 0.0636
BT-20 PHA-665752
0.04
uM
LJP5
 1.0151 0.0047 1.0170 0.0051
BT-20 PHA-665752
0.12
uM
LJP5
 1.0100 0.0265 1.0109 0.0301
BT-20 PHA-665752
0.37
uM
LJP5
 1.0035 0.0043 1.0027 0.0045
BT-20 PHA-665752
1.11
uM
LJP5
 0.9807 0.0199 0.9760 0.0239
BT-20 PHA-665752
3.33
uM
LJP5
 0.9781 0.0160 0.9727 0.0201
BT-20 PHA-665752
10
uM
LJP5
 0.4515 0.1504 0.2202 0.2420
BT-20 PI103
0.04
uM
LJP6
 0.9574 0.0408 0.9487 0.0485
BT-20 PI103
0.12
uM
LJP6
 0.7824 0.1180 0.7231 0.1522
BT-20 PI103
0.37
uM
LJP6
 0.5316 0.1307 0.3569 0.1857
BT-20 PI103
1.11
uM
LJP6
 0.3722 0.0700 0.0983 0.1007
BT-20 PI103
3.33
uM
LJP6
 0.2872 0.0094 -0.0552 0.0098
BT-20 PI103
10
uM
LJP6
 0.2577 0.0079 -0.1150 0.0193
BT-20 Dovitinib
0.04
uM
LJP5
 0.8606 0.0180 0.8301 0.0270
BT-20 Dovitinib
0.12
uM
LJP5
 0.7446 0.0562 0.6853 0.0640
BT-20 Dovitinib
0.37
uM
LJP5
 0.5403 0.0617 0.3937 0.0775
BT-20 Dovitinib
1.11
uM
LJP5
 0.4806 0.0349 0.3038 0.0413
BT-20 Dovitinib
3.33
uM
LJP5
 0.4278 0.0189 0.2190 0.0197
BT-20 Dovitinib
10
uM
LJP5
 0.3923 0.0344 0.1564 0.0673