LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF7 Fedratinib
1.11
uM
LJP5
 0.6277 0.0891 0.5448 0.1299
MCF7 Fedratinib
3.33
uM
LJP5
 0.3258 0.0208 0.0996 0.0663
MCF7 Fedratinib
10
uM
LJP5
 0.1492 0.0020 -0.2722 0.0333
MCF7 Trametinib
0.04
uM
LJP5
 0.4861 0.0190 0.3639 0.0170
MCF7 Trametinib
0.12
uM
LJP5
 0.4874 0.0178 0.3649 0.0158
MCF7 Trametinib
0.37
uM
LJP5
 0.4833 0.0140 0.3596 0.0062
MCF7 Trametinib
1.11
uM
LJP5
 0.5015 0.0295 0.3874 0.0174
MCF7 Trametinib
3.33
uM
LJP5
 0.5291 0.0167 0.4271 0.0044
MCF7 Trametinib
10
uM
LJP5
 0.5284 0.0215 0.4248 0.0075
MCF7 Omipalisib
0.04
uM
LJP6
 0.2895 0.0238 0.0033 0.0319
MCF7 Omipalisib
0.12
uM
LJP6
 0.2843 0.0260 -0.0074 0.0391
MCF7 Omipalisib
0.37
uM
LJP6
 0.2855 0.0314 -0.0055 0.0399
MCF7 Omipalisib
1.11
uM
LJP6
 0.2622 0.0236 -0.0510 0.0178
MCF7 Omipalisib
3.33
uM
LJP6
 0.2421 0.0219 -0.0920 0.0155
MCF7 Omipalisib
10
uM
LJP6
 0.1884 0.0267 -0.2135 0.0344
MCF7 Buparlisib
0.04
uM
LJP5
 0.7984 0.1105 0.7588 0.1432
MCF7 Buparlisib
0.12
uM
LJP5
 0.5705 0.0615 0.4753 0.1016
MCF7 Buparlisib
0.37
uM
LJP5
 0.3523 0.0071 0.1480 0.0399
MCF7 Buparlisib
1.11
uM
LJP5
 0.2166 0.0104 -0.1125 0.0184
MCF7 Buparlisib
3.33
uM
LJP5
 0.1836 0.0164 -0.1880 0.0021
MCF7 Buparlisib
10
uM
LJP5
 0.1837 0.0203 -0.1886 0.0119
MCF7 XL147
0.04
uM
LJP5
 1.1015 0.0213 1.1040 0.0189
MCF7 XL147
0.12
uM
LJP5
 1.0477 0.0155 1.0482 0.0126
MCF7 XL147
0.37
uM
LJP5
 1.0407 0.0141 1.0433 0.0157
MCF7 XL147
1.11
uM
LJP5
 1.0408 0.0057 1.0419 0.0053