LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | Geldanamycin | 0.37 | uM | LJP5 | 0.0849 | 0.0206 | -0.0350 | 0.0257 |
| MCF 10A | Geldanamycin | 0.37 | uM | LJP6 | 0.0729 | 0.0164 | -0.0724 | 0.0368 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 0.0854 | 0.0243 | -0.0376 | 0.0138 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 0.0733 | 0.0185 | -0.0726 | 0.0285 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP5 | 0.0714 | 0.0182 | -0.0863 | 0.0300 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP6 | 0.0631 | 0.0161 | -0.1131 | 0.0299 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 0.0590 | 0.0157 | -0.1384 | 0.0326 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 0.0449 | 0.0144 | -0.2029 | 0.0295 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 1.0265 | 0.0074 | 1.0149 | 0.0033 |
| MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 0.9795 | 0.0133 | 0.9891 | 0.0060 |
| MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 0.9162 | 0.0265 | 0.9507 | 0.0126 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 0.7238 | 0.0509 | 0.8242 | 0.0146 |
| MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 0.6078 | 0.0716 | 0.7345 | 0.0294 |
| MCF 10A | YM 201636 | 10 | uM | LJP5 | 0.2335 | 0.0525 | 0.3008 | 0.0246 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 1.0298 | 0.0140 | 1.0167 | 0.0074 |
| MCF 10A | TWS119 | 0.12 | uM | LJP5 | 1.0127 | 0.0129 | 1.0067 | 0.0066 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 1.0360 | 0.0093 | 1.0203 | 0.0047 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 1.0309 | 0.0223 | 1.0208 | 0.0139 |
| MCF 10A | TWS119 | 3.33 | uM | LJP5 | 0.8434 | 0.1127 | 0.9120 | 0.0610 |
| MCF 10A | TWS119 | 10 | uM | LJP5 | 0.1155 | 0.0443 | 0.0326 | 0.0483 |
| MCF 10A | PF477736 | 0.04 | uM | LJP5 | 0.9306 | 0.0152 | 0.9601 | 0.0050 |
| MCF 10A | PF477736 | 0.12 | uM | LJP5 | 0.8588 | 0.0247 | 0.9142 | 0.0130 |
| MCF 10A | PF477736 | 0.37 | uM | LJP5 | 0.7376 | 0.0338 | 0.8305 | 0.0211 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 0.4938 | 0.0876 | 0.6305 | 0.0413 |
| MCF 10A | PF477736 | 3.33 | uM | LJP5 | 0.2284 | 0.1012 | 0.2674 | 0.0969 |