LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 962 1899 10512 0.1808 0.2180
MCF 10A GDC-0980
1.11
uM
LJP5
 72
hr
 962 1397 10512 0.1329 0.1138
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 962 1254 10512 0.1194 0.0799
MCF 10A GDC-0980
10
uM
LJP5
 72
hr
 962 954 10512 0.0908 -0.0027
MCF 10A Mitoxantrone
0.04
uM
LJP5
 72
hr
 962 2239 10512 0.2129 0.2768
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 962 2046 10692 0.1915 0.2425
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 962 1047 10512 0.0995 0.0240
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 962 1024 10692 0.0958 0.0181
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 962 976 10512 0.0929 0.0037
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 962 972 10692 0.0910 0.0030
MCF 10A Mitoxantrone
1.11
uM
LJP5
 72
hr
 962 884 10512 0.0841 -0.0245
MCF 10A Mitoxantrone
1.11
uM
LJP6
 72
hr
 962 819 10692 0.0766 -0.0454
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 962 380 10512 0.0361 -0.2392
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 962 460 10692 0.0431 -0.1920
MCF 10A Mitoxantrone
10
uM
LJP5
 72
hr
 962 509 10512 0.0484 -0.1687
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 962 552 10692 0.0517 -0.1484
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 962 9600 10512 0.9131 0.9478
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 962 10049 10692 0.9398 0.9645
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 962 6589 10512 0.6265 0.7458
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 962 6550 10692 0.6126 0.7365
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 962 2901 10512 0.2763 0.3757
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 962 2892 10692 0.2705 0.3723
MCF 10A Radicicol
1.11
uM
LJP5
 72
hr
 962 1367 10512 0.1300 0.1036
MCF 10A Radicicol
1.11
uM
LJP6
 72
hr
 962 1324 10692 0.1239 0.0964
MCF 10A Radicicol
3.33
uM
LJP5
 72
hr
 962 760 10512 0.0723 -0.0689