LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PF477736
10
uM
LJP5
 72
hr
 962 821 10512 0.0781 -0.0450
MCF 10A LDN-193189
0.04
uM
LJP5
 72
hr
 962 10223 10512 0.9724 0.9838
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 962 10166 10512 0.9669 0.9804
MCF 10A LDN-193189
0.37
uM
LJP5
 72
hr
 962 9892 10512 0.9410 0.9649
MCF 10A LDN-193189
1.11
uM
LJP5
 72
hr
 962 9905 10512 0.9424 0.9658
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 962 2316 10512 0.2207 0.2876
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 962 136 10512 0.0130 -0.4374
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 962 6508 10512 0.6192 0.7405
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 962 3745 10512 0.3563 0.4828
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 962 1604 10512 0.1525 0.1593
MCF 10A PF431396
1.11
uM
LJP5
 72
hr
 962 1275 10512 0.1214 0.0850
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 962 1103 10512 0.1049 0.0402
MCF 10A PF431396
10
uM
LJP5
 72
hr
 962 413 10512 0.0392 -0.2201
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 962 11411 10692 1.0673 1.0378
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 962 11071 10692 1.0355 1.0202
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 962 9824 10692 0.9189 0.9515
MCF 10A Celastrol
1.11
uM
LJP6
 72
hr
 962 959 10692 0.0897 -0.0022
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 962 374 10692 0.0350 -0.2380
MCF 10A Celastrol
10
uM
LJP6
 72
hr
 962 676 10692 0.0633 -0.0968
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 962 10194 10512 0.9696 0.9821
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 962 9686 10512 0.9212 0.9528
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 962 9108 10512 0.8663 0.9185
MCF 10A SU11274
1.11
uM
LJP5
 72
hr
 962 8235 10512 0.7833 0.8632
MCF 10A SU11274
3.33
uM
LJP5
 72
hr
 962 6858 10512 0.6524 0.7671
MCF 10A SU11274
10
uM
LJP5
 72
hr
 962 3529 10512 0.3357 0.4574