LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 6369 | 5905 | 1.0792 | 1.0747 |
MCF7 | XL147 | 10 | uM | LJP5 | 72 | hr | 1389 | 3984 | 5905 | 0.6736 | 0.6530 |
MCF7 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 5536 | 5445 | 1.0136 | 1.0098 |
MCF7 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 5459 | 5445 | 1.0016 | 0.9998 |
MCF7 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5306 | 5445 | 0.9737 | 0.9721 |
MCF7 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5014 | 5445 | 0.9212 | 0.9181 |
MCF7 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 3883 | 5445 | 0.7127 | 0.6828 |
MCF7 | Y39983 | 10 | uM | LJP6 | 72 | hr | 1389 | 1162 | 5445 | 0.2125 | -0.0925 |
MCF7 | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 1389 | 5303 | 5445 | 0.9709 | 0.9666 |
MCF7 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 4739 | 5445 | 0.8688 | 0.8602 |
MCF7 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 4394 | 5445 | 0.8053 | 0.7884 |
MCF7 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 3670 | 5445 | 0.6737 | 0.6360 |
MCF7 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1389 | 2660 | 5445 | 0.4870 | 0.3854 |
MCF7 | Nintedanib | 10 | uM | LJP6 | 72 | hr | 1389 | 2134 | 5445 | 0.3904 | 0.2333 |
MCF7 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 6042 | 5905 | 1.0226 | 1.0210 |
MCF7 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 3798 | 5905 | 0.6411 | 0.6109 |
MCF7 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 1881 | 5905 | 0.3183 | 0.1552 |
MCF7 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 1405 | 5905 | 0.2378 | 0.0049 |
MCF7 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1375 | 5905 | 0.2326 | -0.0060 |
MCF7 | Foretinib | 10 | uM | LJP5 | 72 | hr | 1389 | 782 | 5905 | 0.1322 | -0.2418 |
MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 4843 | 5445 | 0.8894 | 0.8840 |
MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 3018 | 5445 | 0.5552 | 0.4828 |
MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1573 | 5445 | 0.2889 | 0.0639 |
MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1223 | 5445 | 0.2247 | -0.0634 |
MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 688 | 5445 | 0.1263 | -0.3017 |