LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Linifanib
0.12
uM
LJP6
72
hr
513 11112 10473 1.0611 1.0274
MCF 10A Linifanib
0.37
uM
LJP6
72
hr
513 10979 10473 1.0485 1.0218
MCF 10A Linifanib
1.11
uM
LJP6
72
hr
513 10826 10473 1.0337 1.0152
MCF 10A Linifanib
3.33
uM
LJP6
72
hr
513 9782 10473 0.9340 0.9688
MCF 10A Linifanib
10
uM
LJP6
72
hr
513 2516 10473 0.2403 0.4388
MCF 10A PIK-93
0.04
uM
LJP5
72
hr
513 10310 10362 0.9950 0.9975
MCF 10A PIK-93
0.12
uM
LJP5
72
hr
513 10421 10362 1.0058 1.0025
MCF 10A PIK-93
0.37
uM
LJP5
72
hr
513 10414 10362 1.0052 1.0023
MCF 10A PIK-93
1.11
uM
LJP5
72
hr
513 9444 10362 0.9114 0.9576
MCF 10A PIK-93
3.33
uM
LJP5
72
hr
513 5421 10362 0.5234 0.7223
MCF 10A PIK-93
10
uM
LJP5
72
hr
513 2299 10362 0.2220 0.4129
MCF 10A Dactolisib
0.04
uM
LJP5
72
hr
513 1969 10362 0.1901 0.3634
MCF 10A Dactolisib
0.12
uM
LJP5
72
hr
513 1514 10362 0.1463 0.2790
MCF 10A Dactolisib
0.37
uM
LJP5
72
hr
513 943 10362 0.0911 0.1502
MCF 10A Dactolisib
1.11
uM
LJP5
72
hr
513 991 10362 0.0956 0.1629
MCF 10A Dactolisib
3.33
uM
LJP5
72
hr
513 967 10362 0.0934 0.1569
MCF 10A Dactolisib
10
uM
LJP5
72
hr
513 1157 10362 0.1117 0.2062
MCF 10A Alpelisib
0.04
uM
LJP5
72
hr
513 9455 10362 0.9126 0.9582
MCF 10A Alpelisib
0.12
uM
LJP5
72
hr
513 8470 10362 0.8173 0.9090
MCF 10A Alpelisib
0.37
uM
LJP5
72
hr
513 7173 10362 0.6923 0.8373
MCF 10A Alpelisib
1.11
uM
LJP5
72
hr
513 6513 10362 0.6288 0.7952
MCF 10A Alpelisib
3.33
uM
LJP5
72
hr
513 4552 10362 0.4394 0.6522
MCF 10A Alpelisib
10
uM
LJP5
72
hr
513 1516 10362 0.1464 0.2838
MCF 10A GDC-0980
0.04
uM
LJP5
72
hr
513 5062 10362 0.4888 0.6947
MCF 10A GDC-0980
0.12
uM
LJP5
72
hr
513 2441 10362 0.2354 0.4311