LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 513 | 11112 | 10473 | 1.0611 | 1.0274 |
MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 513 | 10979 | 10473 | 1.0485 | 1.0218 |
MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10826 | 10473 | 1.0337 | 1.0152 |
MCF 10A | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 513 | 9782 | 10473 | 0.9340 | 0.9688 |
MCF 10A | Linifanib | 10 | uM | LJP6 | 72 | hr | 513 | 2516 | 10473 | 0.2403 | 0.4388 |
MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10310 | 10362 | 0.9950 | 0.9975 |
MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10421 | 10362 | 1.0058 | 1.0025 |
MCF 10A | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10414 | 10362 | 1.0052 | 1.0023 |
MCF 10A | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 513 | 9444 | 10362 | 0.9114 | 0.9576 |
MCF 10A | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 513 | 5421 | 10362 | 0.5234 | 0.7223 |
MCF 10A | PIK-93 | 10 | uM | LJP5 | 72 | hr | 513 | 2299 | 10362 | 0.2220 | 0.4129 |
MCF 10A | Dactolisib | 0.04 | uM | LJP5 | 72 | hr | 513 | 1969 | 10362 | 0.1901 | 0.3634 |
MCF 10A | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 513 | 1514 | 10362 | 0.1463 | 0.2790 |
MCF 10A | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 513 | 943 | 10362 | 0.0911 | 0.1502 |
MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 513 | 991 | 10362 | 0.0956 | 0.1629 |
MCF 10A | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 513 | 967 | 10362 | 0.0934 | 0.1569 |
MCF 10A | Dactolisib | 10 | uM | LJP5 | 72 | hr | 513 | 1157 | 10362 | 0.1117 | 0.2062 |
MCF 10A | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 513 | 9455 | 10362 | 0.9126 | 0.9582 |
MCF 10A | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 513 | 8470 | 10362 | 0.8173 | 0.9090 |
MCF 10A | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 513 | 7173 | 10362 | 0.6923 | 0.8373 |
MCF 10A | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 513 | 6513 | 10362 | 0.6288 | 0.7952 |
MCF 10A | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 513 | 4552 | 10362 | 0.4394 | 0.6522 |
MCF 10A | Alpelisib | 10 | uM | LJP5 | 72 | hr | 513 | 1516 | 10362 | 0.1464 | 0.2838 |
MCF 10A | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 513 | 5062 | 10362 | 0.4888 | 0.6947 |
MCF 10A | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 513 | 2441 | 10362 | 0.2354 | 0.4311 |