LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1209 | 2009 | 3980 | 0.5048 | 0.3435 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 2 | L03 | 72 | hr | 1209 | 2224 | 4252 | 0.5230 | 0.3990 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1209 | 2179 | 4376 | 0.4979 | 0.3734 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 1 | L02 | 72 | hr | 1209 | 1376 | 3980 | 0.3457 | 0.0779 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 2 | L02 | 72 | hr | 1209 | 1364 | 4252 | 0.3207 | 0.0685 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 3 | L02 | 72 | hr | 1209 | 1434 | 4376 | 0.3277 | 0.0961 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 1 | L01 | 72 | hr | 1209 | 598 | 3980 | 0.1503 | -0.3363 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 2 | L01 | 72 | hr | 1209 | 641 | 4252 | 0.1507 | -0.2954 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 3 | L01 | 72 | hr | 1209 | 640 | 4376 | 0.1463 | -0.2904 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 1 | P24 | 72 | hr | 1209 | 2044 | 3980 | 0.5136 | 0.3571 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 2 | P24 | 72 | hr | 1209 | 2145 | 4252 | 0.5044 | 0.3714 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 3 | P24 | 72 | hr | 1209 | 2376 | 4376 | 0.5429 | 0.4390 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 1 | P23 | 72 | hr | 1209 | 1977 | 3980 | 0.4967 | 0.3310 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 2 | P23 | 72 | hr | 1209 | 2125 | 4252 | 0.4997 | 0.3643 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 3 | P23 | 72 | hr | 1209 | 1989 | 4376 | 0.4545 | 0.3075 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 1 | P22 | 72 | hr | 1209 | 2051 | 3980 | 0.5153 | 0.3598 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 2 | P22 | 72 | hr | 1209 | 2252 | 4252 | 0.5295 | 0.4087 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 3 | P22 | 72 | hr | 1209 | 1951 | 4376 | 0.4458 | 0.2940 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1209 | 2259 | 3980 | 0.5676 | 0.4384 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 2 | P21 | 72 | hr | 1209 | 2186 | 4252 | 0.5140 | 0.3858 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1209 | 2166 | 4376 | 0.4950 | 0.3690 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 1 | P20 | 72 | hr | 1209 | 2265 | 3980 | 0.5691 | 0.4406 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 2 | P20 | 72 | hr | 1209 | 2419 | 4252 | 0.5688 | 0.4654 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 3 | P20 | 72 | hr | 1209 | 2239 | 4376 | 0.5116 | 0.3936 |
| MCF7 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 1209 | 2162 | 3980 | 0.5432 | 0.4021 |