LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PHA-665752 | 3.33 | uM | LJP5 | 3 | F14 | 72 | hr | 1209 | 4051 | 4376 | 0.9257 | 0.9185 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 1 | F13 | 72 | hr | 1209 | 2450 | 3980 | 0.6156 | 0.5080 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 1209 | 2653 | 4252 | 0.6238 | 0.5419 |
| MCF7 | PHA-665752 | 10 | uM | LJP5 | 3 | F13 | 72 | hr | 1209 | 2438 | 4376 | 0.5571 | 0.4591 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 1 | I18 | 72 | hr | 1209 | 2154 | 3823 | 0.5634 | 0.4157 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 2 | I18 | 72 | hr | 1209 | 2606 | 4093 | 0.6366 | 0.5471 |
| MCF7 | PI103 | 0.04 | uM | LJP6 | 3 | I18 | 72 | hr | 1209 | 3125 | 4121 | 0.7583 | 0.7103 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 1 | I17 | 72 | hr | 1209 | 1472 | 3823 | 0.3850 | 0.1256 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 2 | I17 | 72 | hr | 1209 | 1702 | 4093 | 0.4157 | 0.2143 |
| MCF7 | PI103 | 0.12 | uM | LJP6 | 3 | I17 | 72 | hr | 1209 | 1828 | 4121 | 0.4436 | 0.2630 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 1 | I16 | 72 | hr | 1209 | 1069 | 3823 | 0.2796 | -0.0717 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 2 | I16 | 72 | hr | 1209 | 1134 | 4093 | 0.2770 | -0.0360 |
| MCF7 | PI103 | 0.37 | uM | LJP6 | 3 | I16 | 72 | hr | 1209 | 1312 | 4121 | 0.3184 | 0.0470 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 1 | I15 | 72 | hr | 1209 | 808 | 3823 | 0.2114 | -0.2157 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 2 | I15 | 72 | hr | 1209 | 1091 | 4093 | 0.2665 | -0.0570 |
| MCF7 | PI103 | 1.11 | uM | LJP6 | 3 | I15 | 72 | hr | 1209 | 1124 | 4121 | 0.2727 | -0.0406 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 1 | I14 | 72 | hr | 1209 | 817 | 3823 | 0.2137 | -0.2105 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 2 | I14 | 72 | hr | 1209 | 1012 | 4093 | 0.2472 | -0.0964 |
| MCF7 | PI103 | 3.33 | uM | LJP6 | 3 | I14 | 72 | hr | 1209 | 917 | 4121 | 0.2225 | -0.1449 |
| MCF7 | PI103 | 10 | uM | LJP6 | 1 | I13 | 72 | hr | 1209 | 586 | 3823 | 0.1533 | -0.3537 |
| MCF7 | PI103 | 10 | uM | LJP6 | 2 | I13 | 72 | hr | 1209 | 769 | 4093 | 0.1878 | -0.2270 |
| MCF7 | PI103 | 10 | uM | LJP6 | 3 | I13 | 72 | hr | 1209 | 745 | 4121 | 0.1808 | -0.2397 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 1 | E24 | 72 | hr | 1209 | 3987 | 3980 | 1.0017 | 1.0020 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 2 | E24 | 72 | hr | 1209 | 3978 | 4252 | 0.9354 | 0.9277 |
| MCF7 | Dovitinib | 0.04 | uM | LJP5 | 3 | E24 | 72 | hr | 1209 | 4047 | 4376 | 0.9248 | 0.9175 |