LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 1 | H12 | 72 | hr | 1209 | 4108 | 3823 | 1.0745 | 1.0885 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 2 | H12 | 72 | hr | 1209 | 3723 | 4093 | 0.9094 | 0.8949 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 3 | H12 | 72 | hr | 1209 | 4045 | 4121 | 0.9815 | 0.9790 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 1 | H11 | 72 | hr | 1209 | 3777 | 3823 | 0.9880 | 0.9855 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 2 | H11 | 72 | hr | 1209 | 3541 | 4093 | 0.8650 | 0.8417 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 3 | H11 | 72 | hr | 1209 | 3910 | 4121 | 0.9488 | 0.9414 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 1 | H10 | 72 | hr | 1209 | 3348 | 3823 | 0.8758 | 0.8464 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 2 | H10 | 72 | hr | 1209 | 3467 | 4093 | 0.8469 | 0.8197 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 3 | H10 | 72 | hr | 1209 | 3471 | 4121 | 0.8422 | 0.8150 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 1 | H09 | 72 | hr | 1209 | 2921 | 3823 | 0.7641 | 0.7007 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 2 | H09 | 72 | hr | 1209 | 3155 | 4093 | 0.7707 | 0.7247 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 3 | H09 | 72 | hr | 1209 | 3303 | 4121 | 0.8015 | 0.7648 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 1 | H08 | 72 | hr | 1209 | 2605 | 3823 | 0.6814 | 0.5874 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 2 | H08 | 72 | hr | 1209 | 2700 | 4093 | 0.6595 | 0.5786 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 3 | H08 | 72 | hr | 1209 | 2596 | 4121 | 0.6299 | 0.5401 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1209 | 650 | 3823 | 0.1700 | -0.3121 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1209 | 734 | 4093 | 0.1793 | -0.2472 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1209 | 695 | 4121 | 0.1686 | -0.2690 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 1 | E18 | 72 | hr | 1209 | 3767 | 3980 | 0.9465 | 0.9370 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 2 | E18 | 72 | hr | 1209 | 3880 | 4252 | 0.9123 | 0.9014 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 3 | E18 | 72 | hr | 1209 | 4177 | 4376 | 0.9545 | 0.9504 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1209 | 3187 | 3980 | 0.8007 | 0.7574 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 2 | E17 | 72 | hr | 1209 | 2760 | 4252 | 0.6490 | 0.5759 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1209 | 3396 | 4376 | 0.7760 | 0.7445 |
| MCF7 | NVP-AEW541 | 0.37 | uM | LJP5 | 1 | E16 | 72 | hr | 1209 | 2321 | 3980 | 0.5832 | 0.4613 |