LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 1209 3957 3823 1.0351 1.0419
MCF7 Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 1209 3816 4093 0.9321 0.9217
MCF7 Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 1209 3886 4121 0.9429 0.9346
MCF7 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 1209 3802 3823 0.9945 0.9934
MCF7 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1209 3855 4093 0.9417 0.9328
MCF7 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 1209 3820 4121 0.9269 0.9160
MCF7 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 1209 3995 3823 1.0450 1.0537
MCF7 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 1209 3808 4093 0.9302 0.9194
MCF7 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 1209 4058 4121 0.9847 0.9826
MCF7 Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 1209 3835 3823 1.0031 1.0038
MCF7 Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 1209 3980 4093 0.9722 0.9682
MCF7 Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 1209 3716 4121 0.9017 0.8863
MCF7 Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 1209 2043 3823 0.5344 0.3712
MCF7 Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 1209 2188 4093 0.5345 0.4007
MCF7 Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 1209 2185 4121 0.5302 0.3971
MCF7 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 1209 4454 3980 1.1191 1.1353
MCF7 CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 1209 4593 4252 1.0800 1.0867
MCF7 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 1209 4190 4376 0.9575 0.9537
MCF7 CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 1209 3971 3980 0.9977 0.9974
MCF7 CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 1209 4067 4252 0.9563 0.9514
MCF7 CP466722
0.12
uM
LJP5
 3
I11
 72
hr
 1209 4488 4376 1.0256 1.0274
MCF7 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 1209 4043 3980 1.0158 1.0183
MCF7 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 1209 4216 4252 0.9914 0.9904
MCF7 CP466722
0.37
uM
LJP5
 3
I10
 72
hr
 1209 4211 4376 0.9623 0.9590
MCF7 CP466722
1.11
uM
LJP5
 1
I09
 72
hr
 1209 3723 3980 0.9354 0.9238