LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 658 1637 3769 0.4343 0.4360
Hs 578T PF562271
10
uM
LJP6
 1
F13
 72
hr
 658 502 3705 0.1355 -0.1030
Hs 578T PF562271
10
uM
LJP6
 2
F13
 72
hr
 658 569 3807 0.1494 -0.0559
Hs 578T PF562271
10
uM
LJP6
 3
F13
 72
hr
 658 635 3769 0.1685 -0.0141
Hs 578T PHA-793887
0.04
uM
LJP6
 1
E24
 72
hr
 658 1727 3705 0.4660 0.4724
Hs 578T PHA-793887
0.04
uM
LJP6
 2
E24
 72
hr
 658 1931 3807 0.5072 0.5296
Hs 578T PHA-793887
0.04
uM
LJP6
 3
E24
 72
hr
 658 1844 3769 0.4892 0.5055
Hs 578T PHA-793887
0.12
uM
LJP6
 1
E23
 72
hr
 658 1354 3705 0.3654 0.3355
Hs 578T PHA-793887
0.12
uM
LJP6
 2
E23
 72
hr
 658 1546 3807 0.4060 0.4010
Hs 578T PHA-793887
0.12
uM
LJP6
 3
E23
 72
hr
 658 1577 3769 0.4183 0.4149
Hs 578T PHA-793887
0.37
uM
LJP6
 1
E22
 72
hr
 658 795 3705 0.2145 0.0787
Hs 578T PHA-793887
0.37
uM
LJP6
 2
E22
 72
hr
 658 888 3807 0.2332 0.1255
Hs 578T PHA-793887
0.37
uM
LJP6
 3
E22
 72
hr
 658 990 3769 0.2626 0.1760
Hs 578T PHA-793887
1.11
uM
LJP6
 1
E21
 72
hr
 658 605 3705 0.1633 -0.0332
Hs 578T PHA-793887
1.11
uM
LJP6
 2
E21
 72
hr
 658 506 3807 0.1329 -0.0986
Hs 578T PHA-793887
1.11
uM
LJP6
 3
E21
 72
hr
 658 619 3769 0.1642 -0.0241
Hs 578T PHA-793887
3.33
uM
LJP6
 1
E20
 72
hr
 658 517 3705 0.1395 -0.0923
Hs 578T PHA-793887
3.33
uM
LJP6
 2
E20
 72
hr
 658 561 3807 0.1473 -0.0611
Hs 578T PHA-793887
3.33
uM
LJP6
 3
E20
 72
hr
 658 524 3769 0.1390 -0.0866
Hs 578T PHA-793887
10
uM
LJP6
 1
E19
 72
hr
 658 452 3705 0.1220 -0.1399
Hs 578T PHA-793887
10
uM
LJP6
 2
E19
 72
hr
 658 442 3807 0.1161 -0.1455
Hs 578T PHA-793887
10
uM
LJP6
 3
E19
 72
hr
 658 479 3769 0.1271 -0.1186
Hs 578T QL-X-138
0.04
uM
LJP6
 1
F24
 72
hr
 658 3105 3705 0.8379 0.8630
Hs 578T QL-X-138
0.04
uM
LJP6
 2
F24
 72
hr
 658 3305 3807 0.8680 0.8913
Hs 578T QL-X-138
0.04
uM
LJP6
 3
F24
 72
hr
 658 3238 3769 0.8590 0.8828