LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 658 858 3908 0.2195 0.1087
Hs 578T BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 658 860 3953 0.2175 0.1089
Hs 578T BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 658 867 3938 0.2201 0.1127
Hs 578T BX-912
10
uM
LJP5
 1
L19
 72
hr
 658 535 3908 0.1369 -0.0775
Hs 578T BX-912
10
uM
LJP5
 2
L19
 72
hr
 658 572 3953 0.1447 -0.0528
Hs 578T BX-912
10
uM
LJP5
 3
L19
 72
hr
 658 610 3938 0.1549 -0.0290
Hs 578T Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 658 2553 3705 0.6889 0.7223
Hs 578T Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 658 2691 3807 0.7068 0.7438
Hs 578T Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 658 2590 3769 0.6871 0.7230
Hs 578T Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 658 2246 3705 0.6061 0.6361
Hs 578T Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 658 2499 3807 0.6563 0.6936
Hs 578T Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 658 2159 3769 0.5727 0.6029
Hs 578T Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 658 1963 3705 0.5297 0.5500
Hs 578T Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 658 2002 3807 0.5258 0.5516
Hs 578T Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 658 1964 3769 0.5210 0.5437
Hs 578T Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 658 1825 3705 0.4925 0.5054
Hs 578T Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 658 1823 3807 0.4788 0.4953
Hs 578T Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 658 1736 3769 0.4605 0.4699
Hs 578T Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 658 1553 3705 0.4191 0.4110
Hs 578T Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 658 1623 3807 0.4263 0.4282
Hs 578T Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 658 1428 3769 0.3788 0.3602
Hs 578T Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 658 1203 3705 0.3246 0.2737
Hs 578T Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 658 1240 3807 0.3257 0.2842
Hs 578T Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 658 1206 3769 0.3199 0.2719
Hs 578T MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 658 3241 3705 0.8746 0.8953