LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 1209 1951 4121 0.4734 0.3104
MCF7 Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 1209 1943 3823 0.5082 0.3304
MCF7 Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 1209 1693 4093 0.4136 0.2107
MCF7 Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 1209 1916 4121 0.4649 0.2970
MCF7 Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 1209 1786 3823 0.4672 0.2646
MCF7 Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 1209 1883 4093 0.4600 0.2861
MCF7 Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 1209 1792 4121 0.4348 0.2489
MCF7 PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 1209 3725 3823 0.9744 0.9690
MCF7 PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 1209 3415 4093 0.8342 0.8041
MCF7 PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 1209 3353 4121 0.8136 0.7798
MCF7 PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 1209 2949 3823 0.7714 0.7105
MCF7 PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 1209 2954 4093 0.7216 0.6613
MCF7 PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 1209 3152 4121 0.7648 0.7187
MCF7 PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 1209 2339 3823 0.6118 0.4877
MCF7 PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 1209 2588 4093 0.6322 0.5410
MCF7 PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 1209 2431 4121 0.5899 0.4839
MCF7 PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 1209 1900 3823 0.4970 0.3126
MCF7 PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 1209 1757 4093 0.4292 0.2365
MCF7 PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 1209 1668 4121 0.4047 0.1993
MCF7 PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 1209 1193 3823 0.3121 -0.0083
MCF7 PF562271
3.33
uM
LJP6
 2
F14
 72
hr
 1209 1092 4093 0.2667 -0.0565
MCF7 PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 1209 1091 4121 0.2647 -0.0567
MCF7 PF562271
10
uM
LJP6
 1
F13
 72
hr
 1209 637 3823 0.1666 -0.3204
MCF7 PF562271
10
uM
LJP6
 2
F13
 72
hr
 1209 733 4093 0.1791 -0.2478
MCF7 PF562271
10
uM
LJP6
 3
F13
 72
hr
 1209 734 4121 0.1781 -0.2461