LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 1 | I02 | 72 | hr | 1209 | 3107 | 3980 | 0.7806 | 0.7316 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 2 | I02 | 72 | hr | 1209 | 3190 | 4252 | 0.7501 | 0.7068 |
| MCF7 | AZD-6482 | 3.33 | uM | LJP5 | 3 | I02 | 72 | hr | 1209 | 3137 | 4376 | 0.7168 | 0.6715 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 1 | I01 | 72 | hr | 1209 | 1183 | 3980 | 0.2972 | -0.0128 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 2 | I01 | 72 | hr | 1209 | 1558 | 4252 | 0.3664 | 0.1498 |
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 3 | I01 | 72 | hr | 1209 | 1695 | 4376 | 0.3873 | 0.1995 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 1 | C12 | 72 | hr | 1209 | 3691 | 3980 | 0.9274 | 0.9141 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 2 | C12 | 72 | hr | 1209 | 4265 | 4252 | 1.0029 | 1.0032 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 3 | C12 | 72 | hr | 1209 | 4086 | 4376 | 0.9337 | 0.9274 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 1 | C11 | 72 | hr | 1209 | 3902 | 3980 | 0.9804 | 0.9771 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 2 | C11 | 72 | hr | 1209 | 3808 | 4252 | 0.8954 | 0.8818 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 3 | C11 | 72 | hr | 1209 | 4079 | 4376 | 0.9321 | 0.9256 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 1 | C10 | 72 | hr | 1209 | 3643 | 3980 | 0.9153 | 0.8996 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 2 | C10 | 72 | hr | 1209 | 3696 | 4252 | 0.8691 | 0.8511 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 3 | C10 | 72 | hr | 1209 | 3994 | 4376 | 0.9127 | 0.9039 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 1 | C09 | 72 | hr | 1209 | 3396 | 3980 | 0.8533 | 0.8236 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 2 | C09 | 72 | hr | 1209 | 3517 | 4252 | 0.8270 | 0.8011 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 3 | C09 | 72 | hr | 1209 | 3550 | 4376 | 0.8112 | 0.7867 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 1 | C08 | 72 | hr | 1209 | 2957 | 3980 | 0.7430 | 0.6824 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 2 | C08 | 72 | hr | 1209 | 3139 | 4252 | 0.7381 | 0.6917 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 3 | C08 | 72 | hr | 1209 | 3068 | 4376 | 0.7011 | 0.6516 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 1 | C07 | 72 | hr | 1209 | 1264 | 3980 | 0.3176 | 0.0260 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 2 | C07 | 72 | hr | 1209 | 1169 | 4252 | 0.2749 | -0.0186 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 3 | C07 | 72 | hr | 1209 | 1344 | 4376 | 0.3071 | 0.0585 |
| MCF7 | OSI-027 | 0.04 | uM | LJP6 | 1 | E12 | 72 | hr | 1209 | 3329 | 3823 | 0.8708 | 0.8401 |