LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 BX-912
10
uM
LJP5
 2
L19
 72
hr
 1209 1229 4252 0.2890 0.0088
MCF7 BX-912
10
uM
LJP5
 3
L19
 72
hr
 1209 1152 4376 0.2633 -0.0259
MCF7 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 1209 3062 3823 0.8009 0.7497
MCF7 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 1209 3160 4093 0.7719 0.7263
MCF7 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 1209 3145 4121 0.7631 0.7165
MCF7 Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 1209 2672 3823 0.6989 0.6119
MCF7 Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 1209 2785 4093 0.6803 0.6066
MCF7 Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 1209 2855 4121 0.6928 0.6251
MCF7 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 1209 2139 3823 0.5595 0.4097
MCF7 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 1209 2732 4093 0.6673 0.5892
MCF7 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 1209 2627 4121 0.6374 0.5504
MCF7 Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 1209 2374 3823 0.6210 0.5011
MCF7 Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 1209 2508 4093 0.6126 0.5137
MCF7 Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 1209 2671 4121 0.6481 0.5651
MCF7 Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 1209 2639 3823 0.6903 0.5998
MCF7 Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 1209 2778 4093 0.6786 0.6043
MCF7 Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 1209 2829 4121 0.6865 0.6168
MCF7 Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 1209 2579 3823 0.6746 0.5778
MCF7 Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 1209 2412 4093 0.5892 0.4805
MCF7 Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 1209 2577 4121 0.6253 0.5337
MCF7 MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1209 2396 3823 0.6267 0.5094
MCF7 MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 1209 2250 4093 0.5496 0.4231
MCF7 MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 1209 2629 4121 0.6379 0.5511
MCF7 MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 1209 2265 3823 0.5925 0.4592
MCF7 MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 1209 2394 4093 0.5848 0.4742