LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 2 | A23 | 72 | hr | 1209 | 3561 | 4252 | 0.8373 | 0.8135 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 3 | A23 | 72 | hr | 1209 | 3530 | 4376 | 0.8067 | 0.7813 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 1 | A22 | 72 | hr | 1209 | 2806 | 3980 | 0.7050 | 0.6319 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 2 | A22 | 72 | hr | 1209 | 3168 | 4252 | 0.7449 | 0.7003 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 3 | A22 | 72 | hr | 1209 | 3246 | 4376 | 0.7418 | 0.7025 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 1 | A21 | 72 | hr | 1209 | 1942 | 3980 | 0.4879 | 0.3172 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 2 | A21 | 72 | hr | 1209 | 2313 | 4252 | 0.5439 | 0.4296 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 3 | A21 | 72 | hr | 1209 | 2234 | 4376 | 0.5105 | 0.3920 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 1 | A20 | 72 | hr | 1209 | 1270 | 3980 | 0.3191 | 0.0288 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 2 | A20 | 72 | hr | 1209 | 1373 | 4252 | 0.3229 | 0.0724 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 3 | A20 | 72 | hr | 1209 | 1254 | 4376 | 0.2866 | 0.0196 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 1 | A19 | 72 | hr | 1209 | 924 | 3980 | 0.2322 | -0.1451 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 2 | A19 | 72 | hr | 1209 | 803 | 4252 | 0.1888 | -0.2022 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 3 | A19 | 72 | hr | 1209 | 932 | 4376 | 0.2130 | -0.1311 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 1 | D06 | 72 | hr | 1209 | 4031 | 3823 | 1.0544 | 1.0649 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 2 | D06 | 72 | hr | 1209 | 4445 | 4093 | 1.0858 | 1.0958 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 3 | D06 | 72 | hr | 1209 | 4236 | 4121 | 1.0279 | 1.0313 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1209 | 4108 | 3823 | 1.0745 | 1.0885 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1209 | 3927 | 4093 | 0.9592 | 0.9532 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1209 | 3806 | 4121 | 0.9235 | 0.9120 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 1 | D04 | 72 | hr | 1209 | 3220 | 3823 | 0.8423 | 0.8036 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 2 | D04 | 72 | hr | 1209 | 3311 | 4093 | 0.8088 | 0.7727 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 3 | D04 | 72 | hr | 1209 | 3667 | 4121 | 0.8898 | 0.8722 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 1 | D03 | 72 | hr | 1209 | 2169 | 3823 | 0.5674 | 0.4216 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 2 | D03 | 72 | hr | 1209 | 2836 | 4093 | 0.6928 | 0.6233 |