LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 1 | E11 | 72 | hr | 1401 | 3575 | 3978 | 0.8986 | 0.8628 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 2 | E11 | 72 | hr | 1401 | 3149 | 4213 | 0.7474 | 0.6650 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 3 | E11 | 72 | hr | 1401 | 3128 | 4545 | 0.6881 | 0.6047 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 1 | E10 | 72 | hr | 1401 | 2159 | 3978 | 0.5427 | 0.3325 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 2 | E10 | 72 | hr | 1401 | 2177 | 4213 | 0.5167 | 0.3196 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 3 | E10 | 72 | hr | 1401 | 2156 | 4545 | 0.4743 | 0.2888 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 1 | E09 | 72 | hr | 1401 | 1872 | 3978 | 0.4705 | 0.2120 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 2 | E09 | 72 | hr | 1401 | 1472 | 4213 | 0.3494 | 0.0314 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 3 | E09 | 72 | hr | 1401 | 1635 | 4545 | 0.3597 | 0.0950 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 1401 | 1772 | 3978 | 0.4454 | 0.1686 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 2 | E08 | 72 | hr | 1401 | 1450 | 4213 | 0.3442 | 0.0216 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 1401 | 1343 | 4545 | 0.2954 | -0.0248 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 1 | E07 | 72 | hr | 1401 | 1532 | 3978 | 0.3851 | 0.0609 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 2 | E07 | 72 | hr | 1401 | 1217 | 4213 | 0.2889 | -0.0851 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 3 | E07 | 72 | hr | 1401 | 1286 | 4545 | 0.2829 | -0.0494 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 1401 | 3375 | 4139 | 0.8154 | 0.7551 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 1401 | 3171 | 4095 | 0.7743 | 0.6952 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 1401 | 3133 | 4272 | 0.7333 | 0.6491 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 1401 | 4052 | 4139 | 0.9790 | 0.9730 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1401 | 3291 | 4095 | 0.8036 | 0.7364 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1401 | 3262 | 4272 | 0.7635 | 0.6911 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 1401 | 2060 | 4139 | 0.4977 | 0.2796 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 1401 | 1609 | 4095 | 0.3929 | 0.0933 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 1401 | 1956 | 4272 | 0.4578 | 0.2304 |
| SK-BR-3 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1401 | 1378 | 4139 | 0.3329 | -0.0108 |