LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 XMD16-144
3.33
uM
LJP5
1
M08
72
hr
1401 1852 3978 0.4655 0.2034
SK-BR-3 XMD16-144
3.33
uM
LJP5
2
M08
72
hr
1401 1511 4213 0.3586 0.0485
SK-BR-3 XMD16-144
3.33
uM
LJP5
3
M08
72
hr
1401 1506 4545 0.3313 0.0433
SK-BR-3 XMD16-144
10
uM
LJP5
1
M07
72
hr
1401 1239 3978 0.3114 -0.0786
SK-BR-3 XMD16-144
10
uM
LJP5
2
M07
72
hr
1401 1173 4213 0.2784 -0.1060
SK-BR-3 XMD16-144
10
uM
LJP5
3
M07
72
hr
1401 1101 4545 0.2422 -0.1325
SK-BR-3 Erlotinib
0.04
uM
LJP5
1
M24
72
hr
1401 3693 3978 0.9282 0.9034
SK-BR-3 Erlotinib
0.04
uM
LJP5
2
M24
72
hr
1401 3726 4213 0.8844 0.8510
SK-BR-3 Erlotinib
0.04
uM
LJP5
3
M24
72
hr
1401 3720 4545 0.8183 0.7772
SK-BR-3 Erlotinib
0.12
uM
LJP5
1
M23
72
hr
1401 3725 3978 0.9363 0.9144
SK-BR-3 Erlotinib
0.12
uM
LJP5
2
M23
72
hr
1401 3861 4213 0.9164 0.8930
SK-BR-3 Erlotinib
0.12
uM
LJP5
3
M23
72
hr
1401 4138 4545 0.9103 0.8922
SK-BR-3 Erlotinib
0.37
uM
LJP5
1
M22
72
hr
1401 3776 3978 0.9491 0.9318
SK-BR-3 Erlotinib
0.37
uM
LJP5
2
M22
72
hr
1401 4096 4213 0.9722 0.9648
SK-BR-3 Erlotinib
0.37
uM
LJP5
3
M22
72
hr
1401 4292 4545 0.9441 0.9334
SK-BR-3 Erlotinib
1.11
uM
LJP5
1
M21
72
hr
1401 3710 3978 0.9325 0.9093
SK-BR-3 Erlotinib
1.11
uM
LJP5
2
M21
72
hr
1401 3963 4213 0.9406 0.9243
SK-BR-3 Erlotinib
1.11
uM
LJP5
3
M21
72
hr
1401 4546 4545 1.0000 1.0000
SK-BR-3 Erlotinib
3.33
uM
LJP5
1
M20
72
hr
1401 3419 3978 0.8594 0.8084
SK-BR-3 Erlotinib
3.33
uM
LJP5
2
M20
72
hr
1401 3848 4213 0.9133 0.8890
SK-BR-3 Erlotinib
3.33
uM
LJP5
3
M20
72
hr
1401 3897 4545 0.8573 0.8265
SK-BR-3 Erlotinib
10
uM
LJP5
1
M19
72
hr
1401 1831 3978 0.4602 0.1943
SK-BR-3 Erlotinib
10
uM
LJP5
2
M19
72
hr
1401 2190 4213 0.5198 0.3246
SK-BR-3 Erlotinib
10
uM
LJP5
3
M19
72
hr
1401 2159 4545 0.4749 0.2899
SK-BR-3 Gefitinib
0.04
uM
LJP6
1
N12
72
hr
1401 3986 4139 0.9630 0.9524