LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Dasatinib
1.11
uM
LJP5
 3
D03
 72
hr
 1209 1581 4376 0.3613 0.1553
MCF7 Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 1209 1437 3823 0.3759 0.1094
MCF7 Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 1209 1582 4093 0.3864 0.1649
MCF7 Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 1209 1616 4121 0.3921 0.1780
MCF7 Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 1209 1648 3980 0.4141 0.1972
MCF7 Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 1209 1548 4252 0.3640 0.1457
MCF7 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 1209 1652 4376 0.3775 0.1830
MCF7 Dasatinib
10
uM
LJP6
 1
I01
 72
hr
 1209 1194 3823 0.3123 -0.0078
MCF7 Dasatinib
10
uM
LJP6
 2
I01
 72
hr
 1209 1114 4093 0.2721 -0.0457
MCF7 Dasatinib
10
uM
LJP6
 3
I01
 72
hr
 1209 1386 4121 0.3363 0.0800
MCF7 Dasatinib
10
uM
LJP5
 1
D01
 72
hr
 1209 1579 3980 0.3967 0.1678
MCF7 Dasatinib
10
uM
LJP5
 2
D01
 72
hr
 1209 1833 4252 0.4310 0.2576
MCF7 Dasatinib
10
uM
LJP5
 3
D01
 72
hr
 1209 1569 4376 0.3585 0.1506
MCF7 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 1209 1361 3980 0.3420 0.0711
MCF7 Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 1209 1337 4252 0.3144 0.0568
MCF7 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1209 1362 4376 0.3112 0.0661
MCF7 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1209 1346 3980 0.3382 0.0642
MCF7 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1209 1468 4252 0.3452 0.1127
MCF7 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1209 1423 4376 0.3252 0.0916
MCF7 Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 1209 1273 3980 0.3198 0.0302
MCF7 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1209 1475 4252 0.3468 0.1156
MCF7 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1209 1471 4376 0.3361 0.1113
MCF7 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 1209 1443 3980 0.3626 0.1082
MCF7 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 1209 1355 4252 0.3186 0.0646
MCF7 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 1209 1526 4376 0.3487 0.1335