LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 Tozasertib
1.11
uM
LJP5
3
B15
72
hr
1401 1420 4545 0.3124 0.0077
SK-BR-3 Tozasertib
3.33
uM
LJP5
1
B14
72
hr
1401 1420 3978 0.3569 0.0087
SK-BR-3 Tozasertib
3.33
uM
LJP5
2
B14
72
hr
1401 1463 4213 0.3472 0.0274
SK-BR-3 Tozasertib
3.33
uM
LJP5
3
B14
72
hr
1401 1403 4545 0.3086 0.0006
SK-BR-3 Tozasertib
10
uM
LJP5
1
B13
72
hr
1401 1503 3978 0.3778 0.0475
SK-BR-3 Tozasertib
10
uM
LJP5
2
B13
72
hr
1401 1644 4213 0.3902 0.1057
SK-BR-3 Tozasertib
10
uM
LJP5
3
B13
72
hr
1401 1541 4545 0.3390 0.0575
SK-BR-3 Imatinib
0.04
uM
LJP6
1
N18
72
hr
1401 4420 4139 1.0679 1.0859
SK-BR-3 Imatinib
0.04
uM
LJP6
2
N18
72
hr
1401 4134 4095 1.0094 1.0122
SK-BR-3 Imatinib
0.04
uM
LJP6
3
N18
72
hr
1401 4700 4272 1.1001 1.1222
SK-BR-3 Imatinib
0.12
uM
LJP6
1
N17
72
hr
1401 4416 4139 1.0669 1.0847
SK-BR-3 Imatinib
0.12
uM
LJP6
2
N17
72
hr
1401 4515 4095 1.1025 1.1302
SK-BR-3 Imatinib
0.12
uM
LJP6
3
N17
72
hr
1401 4746 4272 1.1109 1.1351
SK-BR-3 Imatinib
0.37
uM
LJP6
1
N16
72
hr
1401 4823 4139 1.1653 1.2057
SK-BR-3 Imatinib
0.37
uM
LJP6
2
N16
72
hr
1401 4287 4095 1.0468 1.0600
SK-BR-3 Imatinib
0.37
uM
LJP6
3
N16
72
hr
1401 4387 4272 1.0268 1.0332
SK-BR-3 Imatinib
1.11
uM
LJP6
1
N15
72
hr
1401 4619 4139 1.1160 1.1455
SK-BR-3 Imatinib
1.11
uM
LJP6
2
N15
72
hr
1401 4582 4095 1.1188 1.1506
SK-BR-3 Imatinib
1.11
uM
LJP6
3
N15
72
hr
1401 4543 4272 1.0633 1.0779
SK-BR-3 Imatinib
3.33
uM
LJP6
1
N14
72
hr
1401 4458 4139 1.0771 1.0973
SK-BR-3 Imatinib
3.33
uM
LJP6
2
N14
72
hr
1401 4431 4095 1.0820 1.1045
SK-BR-3 Imatinib
3.33
uM
LJP6
3
N14
72
hr
1401 4489 4272 1.0507 1.0625
SK-BR-3 Imatinib
10
uM
LJP6
1
N13
72
hr
1401 4120 4139 0.9954 0.9941
SK-BR-3 Imatinib
10
uM
LJP6
2
N13
72
hr
1401 4159 4095 1.0155 1.0200
SK-BR-3 Imatinib
10
uM
LJP6
3
N13
72
hr
1401 4495 4272 1.0521 1.0642