LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Dasatinib
0.04
uM
LJP6
 1
I06
 72
hr
 1209 1597 3823 0.4177 0.1822
MCF7 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 1209 4190 4376 0.9575 0.9537
MCF7 AZD8055
0.04
uM
LJP6
 3
A12
 72
hr
 1209 1254 4121 0.3043 0.0206
MCF7 AZD8055
0.04
uM
LJP6
 2
A12
 72
hr
 1209 1244 4093 0.3039 0.0161
MCF7 Alvocidib
0.04
uM
LJP6
 3
A18
 72
hr
 1209 681 4121 0.1652 -0.2773
MCF7 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 1209 4768 4252 1.1211 1.1301
MCF7 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 1209 3746 4093 0.9150 0.9015
MCF7 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 1209 3591 3823 0.9393 0.9260
MCF7 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 1209 3898 4121 0.9458 0.9380
MCF7 HG-5-113-01
0.04
uM
LJP5
 1
B12
 72
hr
 1209 3718 3980 0.9342 0.9223
MCF7 AZD7762
0.04
uM
LJP6
 1
L06
 72
hr
 1209 1898 3823 0.4965 0.3118
MCF7 AZD7762
0.04
uM
LJP6
 2
L06
 72
hr
 1209 2009 4093 0.4907 0.3344
MCF7 AZD7762
0.04
uM
LJP6
 3
L06
 72
hr
 1209 1977 4121 0.4797 0.3202
MCF7 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 1209 1892 4093 0.4622 0.2896
MCF7 Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 1209 4217 3980 1.0595 1.0684
MCF7 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 1209 1843 4121 0.4472 0.2689
MCF7 HG-5-88-01
0.04
uM
LJP6
 3
A24
 72
hr
 1209 3271 4121 0.7937 0.7551
MCF7 AZD8055
0.04
uM
LJP6
 1
A12
 72
hr
 1209 1100 3823 0.2877 -0.0556
MCF7 CP724714
0.04
uM
LJP5
 3
A12
 72
hr
 1209 3823 4376 0.8736 0.8595
MCF7 CP724714
0.04
uM
LJP5
 2
A12
 72
hr
 1209 3767 4252 0.8858 0.8706
MCF7 CP724714
0.04
uM
LJP5
 1
A12
 72
hr
 1209 3849 3980 0.9671 0.9614
MCF7 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 1209 4350 4376 0.9940 0.9936
MCF7 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 1209 4454 3980 1.1191 1.1353
MCF7 Tozasertib
0.04
uM
LJP5
 2
B18
 72
hr
 1209 1337 4252 0.3144 0.0568
MCF7 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 1209 1361 3980 0.3420 0.0711