LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Radicicol
3.33
uM
LJP5
 1
K08
 72
hr
 1209 1421 3980 0.3570 0.0983
MCF7 Radicicol
3.33
uM
LJP5
 2
K08
 72
hr
 1209 1581 4252 0.3718 0.1591
MCF7 Radicicol
3.33
uM
LJP5
 3
K08
 72
hr
 1209 1287 4376 0.2941 0.0340
MCF7 Radicicol
10
uM
LJP6
 1
K07
 72
hr
 1209 946 3823 0.2475 -0.1376
MCF7 Radicicol
10
uM
LJP6
 2
K07
 72
hr
 1209 1016 4093 0.2482 -0.0944
MCF7 Radicicol
10
uM
LJP6
 3
K07
 72
hr
 1209 901 4121 0.2186 -0.1534
MCF7 Radicicol
10
uM
LJP5
 1
K07
 72
hr
 1209 1023 3980 0.2570 -0.0929
MCF7 Radicicol
10
uM
LJP5
 2
K07
 72
hr
 1209 1082 4252 0.2544 -0.0596
MCF7 Radicicol
10
uM
LJP5
 3
K07
 72
hr
 1209 925 4376 0.2114 -0.1346
MCF7 Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 1209 3735 3823 0.9770 0.9721
MCF7 Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 1209 4124 4093 1.0074 1.0084
MCF7 Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 1209 4286 4121 1.0400 1.0448
MCF7 Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 1209 4080 3980 1.0251 1.0291
MCF7 Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 1209 4210 4252 0.9899 0.9889
MCF7 Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 1209 4115 4376 0.9403 0.9348
MCF7 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1209 3497 3823 0.9147 0.8955
MCF7 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1209 3327 4093 0.8127 0.7775
MCF7 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1209 3556 4121 0.8629 0.8400
MCF7 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1209 4585 3980 1.1520 1.1717
MCF7 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1209 4101 4252 0.9643 0.9603
MCF7 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1209 4458 4376 1.0187 1.0201
MCF7 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1209 1717 3823 0.4491 0.2349
MCF7 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1209 1723 4093 0.4209 0.2228
MCF7 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1209 1649 4121 0.4001 0.1915
MCF7 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1209 1694 3980 0.4256 0.2166