LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 1 | K22 | 72 | hr | 1209 | 1044 | 3980 | 0.2623 | -0.0821 |
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 2 | K22 | 72 | hr | 1209 | 991 | 4252 | 0.2330 | -0.1041 |
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 3 | K22 | 72 | hr | 1209 | 1036 | 4376 | 0.2367 | -0.0801 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 1 | K21 | 72 | hr | 1209 | 1097 | 3980 | 0.2756 | -0.0553 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 2 | K21 | 72 | hr | 1209 | 1012 | 4252 | 0.2380 | -0.0936 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1209 | 969 | 4376 | 0.2214 | -0.1127 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 1 | K20 | 72 | hr | 1209 | 978 | 3980 | 0.2457 | -0.1163 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 2 | K20 | 72 | hr | 1209 | 1032 | 4252 | 0.2427 | -0.0838 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1209 | 1002 | 4376 | 0.2290 | -0.0965 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 1 | K19 | 72 | hr | 1209 | 1033 | 3980 | 0.2595 | -0.0877 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 2 | K19 | 72 | hr | 1209 | 1100 | 4252 | 0.2587 | -0.0510 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 3 | K19 | 72 | hr | 1209 | 1117 | 4376 | 0.2553 | -0.0420 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 1 | C24 | 72 | hr | 1209 | 1266 | 3823 | 0.3312 | 0.0279 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 2 | C24 | 72 | hr | 1209 | 1203 | 4093 | 0.2939 | -0.0031 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 3 | C24 | 72 | hr | 1209 | 1305 | 4121 | 0.3167 | 0.0439 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 1 | C24 | 72 | hr | 1209 | 1199 | 3980 | 0.3013 | -0.0051 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 2 | C24 | 72 | hr | 1209 | 1236 | 4252 | 0.2906 | 0.0120 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 3 | C24 | 72 | hr | 1209 | 1284 | 4376 | 0.2934 | 0.0327 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1209 | 1341 | 3823 | 0.3508 | 0.0641 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1209 | 1201 | 4093 | 0.2934 | -0.0040 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1209 | 1167 | 4121 | 0.2832 | -0.0200 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1209 | 1315 | 3980 | 0.3304 | 0.0498 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1209 | 1242 | 4252 | 0.2920 | 0.0147 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1209 | 1255 | 4376 | 0.2868 | 0.0201 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 1 | C22 | 72 | hr | 1209 | 1270 | 3823 | 0.3322 | 0.0298 |