LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 962 9045 10641 0.8500 0.9084
MCF 10A Y39983
10
uM
LJP6
 1
P01
 72
hr
 962 4138 10693 0.3870 0.5218
MCF 10A Y39983
10
uM
LJP6
 2
P01
 72
hr
 962 3752 10740 0.3493 0.4784
MCF 10A Y39983
10
uM
LJP6
 3
P01
 72
hr
 962 4930 10641 0.4633 0.6020
MCF 10A Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 962 10984 10693 1.0272 1.0155
MCF 10A Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 962 11006 10740 1.0247 1.0141
MCF 10A Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 962 10900 10641 1.0243 1.0139
MCF 10A Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 962 10881 10693 1.0175 1.0100
MCF 10A Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 962 10820 10740 1.0074 1.0042
MCF 10A Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 962 10428 10641 0.9799 0.9883
MCF 10A Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 962 10546 10693 0.9862 0.9920
MCF 10A Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 962 10996 10740 1.0238 1.0135
MCF 10A Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 962 10320 10641 0.9698 0.9824
MCF 10A Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 962 10595 10693 0.9908 0.9947
MCF 10A Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 962 10685 10740 0.9948 0.9970
MCF 10A Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 962 10561 10641 0.9924 0.9956
MCF 10A Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 962 10696 10693 1.0002 1.0001
MCF 10A Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 962 10844 10740 1.0096 1.0055
MCF 10A Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 962 10446 10641 0.9816 0.9893
MCF 10A Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 962 10304 10693 0.9636 0.9788
MCF 10A Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 962 10386 10740 0.9670 0.9808
MCF 10A Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 962 10494 10641 0.9861 0.9920
MCF 10A Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 962 10598 10714 0.9892 0.9938
MCF 10A Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 962 10272 10507 0.9776 0.9869
MCF 10A Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 962 10241 10315 0.9928 0.9958