LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 1 | N15 | 72 | hr | 1209 | 3726 | 3980 | 0.9362 | 0.9247 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 2 | N15 | 72 | hr | 1209 | 4118 | 4252 | 0.9683 | 0.9648 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 1209 | 4120 | 4376 | 0.9415 | 0.9360 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 1 | N14 | 72 | hr | 1209 | 3815 | 3980 | 0.9585 | 0.9513 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 2 | N14 | 72 | hr | 1209 | 3828 | 4252 | 0.9001 | 0.8873 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 3 | N14 | 72 | hr | 1209 | 3846 | 4376 | 0.8789 | 0.8655 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 1 | N13 | 72 | hr | 1209 | 915 | 3980 | 0.2299 | -0.1499 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 2 | N13 | 72 | hr | 1209 | 1008 | 4252 | 0.2370 | -0.0956 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 3 | N13 | 72 | hr | 1209 | 950 | 4376 | 0.2171 | -0.1221 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 1 | K24 | 72 | hr | 1209 | 3088 | 3823 | 0.8077 | 0.7586 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 2 | K24 | 72 | hr | 1209 | 3338 | 4093 | 0.8154 | 0.7809 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 3 | K24 | 72 | hr | 1209 | 3599 | 4121 | 0.8733 | 0.8525 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 1 | K23 | 72 | hr | 1209 | 2583 | 3823 | 0.6757 | 0.5793 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 2 | K23 | 72 | hr | 1209 | 3412 | 4093 | 0.8334 | 0.8032 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 3 | K23 | 72 | hr | 1209 | 3304 | 4121 | 0.8017 | 0.7651 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 1 | K22 | 72 | hr | 1209 | 1373 | 3823 | 0.3591 | 0.0793 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 2 | K22 | 72 | hr | 1209 | 1518 | 4093 | 0.3708 | 0.1378 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 3 | K22 | 72 | hr | 1209 | 1622 | 4121 | 0.3936 | 0.1805 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 1 | K21 | 72 | hr | 1209 | 434 | 3823 | 0.1135 | -0.4606 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 2 | K21 | 72 | hr | 1209 | 466 | 4093 | 0.1138 | -0.4186 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 3 | K21 | 72 | hr | 1209 | 481 | 4121 | 0.1167 | -0.4063 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 1 | K20 | 72 | hr | 1209 | 326 | 3823 | 0.0853 | -0.5460 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 2 | K20 | 72 | hr | 1209 | 355 | 4093 | 0.0867 | -0.5019 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 3 | K20 | 72 | hr | 1209 | 378 | 4121 | 0.0917 | -0.4819 |
| MCF7 | JNK-9L | 10 | uM | LJP6 | 1 | K19 | 72 | hr | 1209 | 207 | 3823 | 0.0541 | -0.6547 |