LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SB590885
3.33
uM
LJP5
 2
L14
 72
hr
 658 3976 3953 1.0056 1.0044
Hs 578T SB590885
3.33
uM
LJP5
 3
L14
 72
hr
 658 3887 3938 0.9869 0.9898
Hs 578T SB590885
10
uM
LJP5
 1
L13
 72
hr
 658 124 3908 0.0317 -0.4777
Hs 578T SB590885
10
uM
LJP5
 2
L13
 72
hr
 658 118 3953 0.0298 -0.4855
Hs 578T SB590885
10
uM
LJP5
 3
L13
 72
hr
 658 135 3938 0.0343 -0.4587
Hs 578T Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 658 2804 3705 0.7566 0.7884
Hs 578T Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 658 3076 3807 0.8079 0.8384
Hs 578T Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 658 2982 3769 0.7910 0.8222
Hs 578T Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 658 2455 3705 0.6625 0.6955
Hs 578T Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 658 2567 3807 0.6742 0.7117
Hs 578T Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 658 2493 3769 0.6613 0.6971
Hs 578T Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 658 2413 3705 0.6511 0.6838
Hs 578T Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 658 2356 3807 0.6188 0.6546
Hs 578T Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 658 2397 3769 0.6359 0.6708
Hs 578T Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 658 2144 3705 0.5785 0.6059
Hs 578T Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 658 2164 3807 0.5683 0.6000
Hs 578T Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 658 1993 3769 0.5287 0.5527
Hs 578T Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 658 1843 3705 0.4973 0.5113
Hs 578T Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 658 1835 3807 0.4819 0.4991
Hs 578T Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 658 1945 3769 0.5160 0.5378
Hs 578T Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 658 1276 3705 0.3443 0.3041
Hs 578T Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 658 1360 3807 0.3572 0.3319
Hs 578T Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 658 1365 3769 0.3621 0.3360
Hs 578T PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 658 3360 3908 0.8597 0.8857
Hs 578T PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 658 3396 3953 0.8589 0.8858