LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T AZD8055
10
uM
LJP6
 3
A07
 72
hr
 658 80 3769 0.0212 -0.5670
Hs 578T Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 658 3944 3705 1.0643 1.0506
Hs 578T Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 658 3924 3807 1.0306 1.0239
Hs 578T Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 658 4034 3769 1.0701 1.0546
Hs 578T Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 658 4092 3705 1.1042 1.0811
Hs 578T Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 658 4240 3807 1.1136 1.0868
Hs 578T Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 658 4083 3769 1.0831 1.0644
Hs 578T Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 658 4048 3705 1.0923 1.0721
Hs 578T Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 658 3931 3807 1.0324 1.0254
Hs 578T Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 658 4050 3769 1.0744 1.0578
Hs 578T Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 658 3969 3705 1.0710 1.0558
Hs 578T Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 658 4054 3807 1.0647 1.0501
Hs 578T Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 658 3827 3769 1.0152 1.0120
Hs 578T Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 658 3855 3705 1.0402 1.0319
Hs 578T Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 658 3892 3807 1.0222 1.0174
Hs 578T Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 658 3910 3769 1.0372 1.0292
Hs 578T Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 658 2826 3705 0.7626 0.7940
Hs 578T Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 658 2721 3807 0.7146 0.7515
Hs 578T Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 658 2708 3769 0.7184 0.7538
Hs 578T CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 658 4016 3908 1.0275 1.0212
Hs 578T CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 658 4171 3953 1.0550 1.0418
Hs 578T CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 658 4216 3938 1.0705 1.0535
Hs 578T CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 658 3845 3908 0.9838 0.9873
Hs 578T CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 658 4163 3953 1.0529 1.0403
Hs 578T CP466722
0.12
uM
LJP5
 3
I11
 72
hr
 658 4177 3938 1.0606 1.0461