LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 2 | D17 | 72 | hr | 1209 | 4405 | 4252 | 1.0358 | 1.0392 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 3 | D17 | 72 | hr | 1209 | 4516 | 4376 | 1.0320 | 1.0342 |
| MCF7 | Enzastaurin | 0.37 | uM | LJP5 | 1 | D16 | 72 | hr | 1209 | 3740 | 3980 | 0.9397 | 0.9289 |
| MCF7 | Enzastaurin | 0.37 | uM | LJP5 | 2 | D16 | 72 | hr | 1209 | 4159 | 4252 | 0.9780 | 0.9756 |
| MCF7 | Enzastaurin | 0.37 | uM | LJP5 | 3 | D16 | 72 | hr | 1209 | 4379 | 4376 | 1.0007 | 1.0007 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 1 | D15 | 72 | hr | 1209 | 4065 | 3980 | 1.0213 | 1.0247 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 2 | D15 | 72 | hr | 1209 | 3678 | 4252 | 0.8648 | 0.8461 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 3 | D15 | 72 | hr | 1209 | 4134 | 4376 | 0.9447 | 0.9396 |
| MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 1209 | 4005 | 3980 | 1.0063 | 1.0073 |
| MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 2 | D14 | 72 | hr | 1209 | 3797 | 4252 | 0.8928 | 0.8788 |
| MCF7 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1209 | 3950 | 4376 | 0.9026 | 0.8925 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 1 | D13 | 72 | hr | 1209 | 2880 | 3980 | 0.7236 | 0.6568 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 2 | D13 | 72 | hr | 1209 | 2860 | 4252 | 0.6725 | 0.6071 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 3 | D13 | 72 | hr | 1209 | 2995 | 4376 | 0.6844 | 0.6303 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 1 | E18 | 72 | hr | 1209 | 2919 | 3823 | 0.7635 | 0.7000 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 2 | E18 | 72 | hr | 1209 | 2655 | 4093 | 0.6485 | 0.5636 |
| MCF7 | Palbociclib | 0.04 | uM | LJP6 | 3 | E18 | 72 | hr | 1209 | 2709 | 4121 | 0.6573 | 0.5776 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 1209 | 2473 | 3823 | 0.6469 | 0.5384 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 1209 | 2346 | 4093 | 0.5731 | 0.4573 |
| MCF7 | Palbociclib | 0.12 | uM | LJP6 | 3 | E17 | 72 | hr | 1209 | 2298 | 4121 | 0.5576 | 0.4375 |
| MCF7 | Palbociclib | 0.37 | uM | LJP6 | 1 | E16 | 72 | hr | 1209 | 1987 | 3823 | 0.5198 | 0.3485 |
| MCF7 | Palbociclib | 0.37 | uM | LJP6 | 2 | E16 | 72 | hr | 1209 | 2040 | 4093 | 0.4983 | 0.3460 |
| MCF7 | Palbociclib | 0.37 | uM | LJP6 | 3 | E16 | 72 | hr | 1209 | 2039 | 4121 | 0.4948 | 0.3435 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 1 | E15 | 72 | hr | 1209 | 1970 | 3823 | 0.5153 | 0.3415 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 2 | E15 | 72 | hr | 1209 | 2048 | 4093 | 0.5003 | 0.3490 |