LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 1097 1102 3877 0.2842 0.0024
BT-20 Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 1097 1280 3925 0.3261 0.0874
BT-20 Mitoxantrone
0.37
uM
LJP6
 1
C22
 72
hr
 1097 1084 3610 0.3002 -0.0070
BT-20 Mitoxantrone
0.37
uM
LJP6
 2
C22
 72
hr
 1097 973 3713 0.2620 -0.0660
BT-20 Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 1097 926 3696 0.2505 -0.0923
BT-20 Mitoxantrone
0.37
uM
LJP5
 1
C22
 72
hr
 1097 883 3735 0.2364 -0.1157
BT-20 Mitoxantrone
0.37
uM
LJP5
 2
C22
 72
hr
 1097 912 3877 0.2352 -0.0965
BT-20 Mitoxantrone
0.37
uM
LJP5
 3
C22
 72
hr
 1097 956 3925 0.2435 -0.0722
BT-20 Mitoxantrone
1.11
uM
LJP6
 1
C21
 72
hr
 1097 860 3610 0.2382 -0.1322
BT-20 Mitoxantrone
1.11
uM
LJP6
 2
C21
 72
hr
 1097 682 3713 0.1836 -0.2369
BT-20 Mitoxantrone
1.11
uM
LJP6
 3
C21
 72
hr
 1097 826 3696 0.2235 -0.1496
BT-20 Mitoxantrone
1.11
uM
LJP5
 1
C21
 72
hr
 1097 851 3735 0.2278 -0.1340
BT-20 Mitoxantrone
1.11
uM
LJP5
 2
C21
 72
hr
 1097 800 3877 0.2063 -0.1593
BT-20 Mitoxantrone
1.11
uM
LJP5
 3
C21
 72
hr
 1097 728 3925 0.1855 -0.2000
BT-20 Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 1097 753 3610 0.2086 -0.1968
BT-20 Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 1097 621 3713 0.1672 -0.2765
BT-20 Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 1097 599 3696 0.1621 -0.2921
BT-20 Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 1097 665 3735 0.1780 -0.2468
BT-20 Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 1097 777 3877 0.2004 -0.1726
BT-20 Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 1097 632 3925 0.1610 -0.2592
BT-20 Mitoxantrone
10
uM
LJP6
 1
C19
 72
hr
 1097 224 3610 0.0620 -0.6034
BT-20 Mitoxantrone
10
uM
LJP6
 2
C19
 72
hr
 1097 194 3713 0.0522 -0.6266
BT-20 Mitoxantrone
10
uM
LJP6
 3
C19
 72
hr
 1097 187 3696 0.0506 -0.6357
BT-20 Mitoxantrone
10
uM
LJP5
 1
C19
 72
hr
 1097 168 3735 0.0450 -0.6542
BT-20 Mitoxantrone
10
uM
LJP5
 2
C19
 72
hr
 1097 124 3877 0.0320 -0.6979