LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 1097 4108 3877 1.0594 1.0643
BT-20 PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 1097 3692 3925 0.9405 0.9344
BT-20 PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 1097 3332 3735 0.8921 0.8748
BT-20 PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 1097 3605 3877 0.9297 0.9215
BT-20 PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 1097 3566 3925 0.9084 0.8982
BT-20 PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 1097 2999 3735 0.8029 0.7664
BT-20 PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 1097 3082 3877 0.7948 0.7630
BT-20 PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 1097 2940 3925 0.7490 0.7091
BT-20 PIK-93
10
uM
LJP5
 1
K13
 72
hr
 1097 1362 3735 0.3646 0.1301
BT-20 PIK-93
10
uM
LJP5
 2
K13
 72
hr
 1097 1365 3877 0.3520 0.1274
BT-20 PIK-93
10
uM
LJP5
 3
K13
 72
hr
 1097 1357 3925 0.3457 0.1225
BT-20 Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 1097 1456 3735 0.3898 0.1736
BT-20 Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 1097 1381 3877 0.3561 0.1346
BT-20 Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 1097 1339 3925 0.3411 0.1144
BT-20 Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 1097 1192 3735 0.3191 0.0480
BT-20 Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 1097 1059 3877 0.2731 -0.0193
BT-20 Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 1097 1043 3925 0.2657 -0.0272
BT-20 Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 1097 1110 3735 0.2972 0.0066
BT-20 Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 1097 1016 3877 0.2620 -0.0414
BT-20 Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 1097 1035 3925 0.2637 -0.0313
BT-20 Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 1097 1382 3735 0.3700 0.1395
BT-20 Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 1097 1186 3877 0.3058 0.0436
BT-20 Dactolisib
1.11
uM
LJP5
 3
M15
 72
hr
 1097 1125 3925 0.2866 0.0137
BT-20 Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 1097 1376 3735 0.3684 0.1367
BT-20 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 1097 1313 3877 0.3386 0.1036