LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 1209 3132 4093 0.7651 0.7175
MCF7 OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 1209 3116 4121 0.7561 0.7075
MCF7 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1209 2443 3823 0.6390 0.5272
MCF7 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1209 2337 4093 0.5709 0.4542
MCF7 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1209 2296 4121 0.5571 0.4368
MCF7 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1209 2079 3823 0.5438 0.3858
MCF7 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1209 1861 4093 0.4546 0.2776
MCF7 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1209 1935 4121 0.4695 0.3043
MCF7 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1209 1671 3823 0.4371 0.2149
MCF7 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1209 1482 4093 0.3620 0.1224
MCF7 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1209 1684 4121 0.4086 0.2058
MCF7 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1209 1590 3823 0.4159 0.1791
MCF7 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1209 1461 4093 0.3569 0.1134
MCF7 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1209 1326 4121 0.3218 0.0533
MCF7 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1209 1217 3823 0.3183 0.0037
MCF7 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1209 1259 4093 0.3075 0.0230
MCF7 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1209 1291 4121 0.3133 0.0375
MCF7 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1209 1268 3823 0.3317 0.0288
MCF7 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1209 1275 4093 0.3114 0.0304
MCF7 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1209 1459 4121 0.3540 0.1118
MCF7 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1209 1197 3823 0.3131 -0.0063
MCF7 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1209 1342 4093 0.3278 0.0609
MCF7 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1209 1254 4121 0.3043 0.0206
MCF7 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1209 1282 3823 0.3353 0.0357
MCF7 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1209 1340 4093 0.3273 0.0600