LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 BMS345541
1.11
uM
LJP6
 3
D03
 72
hr
 1209 2502 4121 0.6071 0.5083
MCF7 BMS345541
3.33
uM
LJP6
 1
D02
 72
hr
 1209 1424 3823 0.3725 0.1033
MCF7 BMS345541
3.33
uM
LJP6
 2
D02
 72
hr
 1209 1323 4093 0.3232 0.0523
MCF7 BMS345541
3.33
uM
LJP6
 3
D02
 72
hr
 1209 1536 4121 0.3727 0.1447
MCF7 BMS345541
10
uM
LJP6
 1
D01
 72
hr
 1209 462 3823 0.1209 -0.4399
MCF7 BMS345541
10
uM
LJP6
 2
D01
 72
hr
 1209 496 4093 0.1212 -0.3976
MCF7 BMS345541
10
uM
LJP6
 3
D01
 72
hr
 1209 552 4121 0.1339 -0.3583
MCF7 KIN001-043
0.04
uM
LJP6
 1
C12
 72
hr
 1209 3848 3823 1.0065 1.0079
MCF7 KIN001-043
0.04
uM
LJP6
 2
C12
 72
hr
 1209 3506 4093 0.8564 0.8313
MCF7 KIN001-043
0.04
uM
LJP6
 3
C12
 72
hr
 1209 3531 4121 0.8568 0.8326
MCF7 KIN001-043
0.12
uM
LJP6
 1
C11
 72
hr
 1209 3540 3823 0.9260 0.9095
MCF7 KIN001-043
0.12
uM
LJP6
 2
C11
 72
hr
 1209 3196 4093 0.7807 0.7374
MCF7 KIN001-043
0.12
uM
LJP6
 3
C11
 72
hr
 1209 3047 4121 0.7394 0.6861
MCF7 KIN001-043
0.37
uM
LJP6
 1
C10
 72
hr
 1209 3329 3823 0.8708 0.8401
MCF7 KIN001-043
0.37
uM
LJP6
 2
C10
 72
hr
 1209 3077 4093 0.7516 0.7003
MCF7 KIN001-043
0.37
uM
LJP6
 3
C10
 72
hr
 1209 3072 4121 0.7454 0.6939
MCF7 KIN001-043
1.11
uM
LJP6
 1
C09
 72
hr
 1209 3342 3823 0.8742 0.8444
MCF7 KIN001-043
1.11
uM
LJP6
 2
C09
 72
hr
 1209 3419 4093 0.8352 0.8053
MCF7 KIN001-043
1.11
uM
LJP6
 3
C09
 72
hr
 1209 3374 4121 0.8187 0.7861
MCF7 KIN001-043
3.33
uM
LJP6
 1
C08
 72
hr
 1209 3290 3823 0.8606 0.8271
MCF7 KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 1209 2908 4093 0.7103 0.6466
MCF7 KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 1209 3180 4121 0.7716 0.7273
MCF7 KIN001-043
10
uM
LJP6
 1
C07
 72
hr
 1209 1640 3823 0.4290 0.2013
MCF7 KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 1209 1528 4093 0.3732 0.1421
MCF7 KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 1209 1673 4121 0.4060 0.2013