LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 2 | M13 | 72 | hr | 1401 | 1707 | 4213 | 0.4052 | 0.1322 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 3 | M13 | 72 | hr | 1401 | 1540 | 4545 | 0.3388 | 0.0571 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 1401 | 3961 | 3978 | 0.9956 | 0.9941 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 2 | N06 | 72 | hr | 1401 | 4033 | 4213 | 0.9572 | 0.9457 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 1401 | 4394 | 4545 | 0.9666 | 0.9604 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1401 | 3616 | 3978 | 0.9089 | 0.8770 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 2 | N05 | 72 | hr | 1401 | 3814 | 4213 | 0.9052 | 0.8785 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 3 | N05 | 72 | hr | 1401 | 4069 | 4545 | 0.8951 | 0.8736 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 1401 | 3145 | 3978 | 0.7905 | 0.7108 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 2 | N04 | 72 | hr | 1401 | 3544 | 4213 | 0.8412 | 0.7936 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 1401 | 3337 | 4545 | 0.7341 | 0.6670 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1401 | 2682 | 3978 | 0.6741 | 0.5390 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1401 | 2923 | 4213 | 0.6938 | 0.5887 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1401 | 3143 | 4545 | 0.6914 | 0.6092 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1401 | 2423 | 3978 | 0.6090 | 0.4386 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 1401 | 2548 | 4213 | 0.6048 | 0.4571 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1401 | 2667 | 4545 | 0.5867 | 0.4608 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 1 | N01 | 72 | hr | 1401 | 1436 | 3978 | 0.3609 | 0.0163 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 2 | N01 | 72 | hr | 1401 | 1729 | 4213 | 0.4104 | 0.1414 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 3 | N01 | 72 | hr | 1401 | 1616 | 4545 | 0.3555 | 0.0875 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 1 | K24 | 72 | hr | 1401 | 1861 | 3978 | 0.4678 | 0.2073 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 2 | K24 | 72 | hr | 1401 | 1935 | 4213 | 0.4593 | 0.2252 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 3 | K24 | 72 | hr | 1401 | 2027 | 4545 | 0.4459 | 0.2428 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1401 | 1402 | 3978 | 0.3524 | 0.0002 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1401 | 1516 | 4213 | 0.3598 | 0.0507 |