LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 1401 | 3293 | 3978 | 0.8277 | 0.7639 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 2 | P19 | 72 | hr | 1401 | 3536 | 4213 | 0.8393 | 0.7910 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 3 | P19 | 72 | hr | 1401 | 4014 | 4545 | 0.8830 | 0.8586 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 1 | N06 | 72 | hr | 1401 | 1395 | 4139 | 0.3370 | -0.0030 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 2 | N06 | 72 | hr | 1401 | 1370 | 4095 | 0.3345 | -0.0146 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 3 | N06 | 72 | hr | 1401 | 1454 | 4272 | 0.3403 | 0.0231 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 1 | N05 | 72 | hr | 1401 | 1260 | 4139 | 0.3044 | -0.0659 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 2 | N05 | 72 | hr | 1401 | 1441 | 4095 | 0.3519 | 0.0181 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 3 | N05 | 72 | hr | 1401 | 1386 | 4272 | 0.3244 | -0.0069 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 1 | N04 | 72 | hr | 1401 | 1211 | 4139 | 0.2926 | -0.0893 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 2 | N04 | 72 | hr | 1401 | 1265 | 4095 | 0.3089 | -0.0641 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 3 | N04 | 72 | hr | 1401 | 1357 | 4272 | 0.3176 | -0.0199 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 1 | N03 | 72 | hr | 1401 | 1133 | 4139 | 0.2737 | -0.1273 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 2 | N03 | 72 | hr | 1401 | 1054 | 4095 | 0.2574 | -0.1682 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 3 | N03 | 72 | hr | 1401 | 1191 | 4272 | 0.2788 | -0.0963 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 1 | N02 | 72 | hr | 1401 | 807 | 4139 | 0.1950 | -0.2977 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 2 | N02 | 72 | hr | 1401 | 916 | 4095 | 0.2237 | -0.2404 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 3 | N02 | 72 | hr | 1401 | 1049 | 4272 | 0.2455 | -0.1649 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 1401 | 808 | 4139 | 0.1952 | -0.2971 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 2 | N01 | 72 | hr | 1401 | 848 | 4095 | 0.2071 | -0.2773 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 1401 | 909 | 4272 | 0.2128 | -0.2361 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 1 | H06 | 72 | hr | 1401 | 3430 | 3978 | 0.8621 | 0.8123 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 2 | H06 | 72 | hr | 1401 | 3897 | 4213 | 0.9249 | 0.9041 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 3 | H06 | 72 | hr | 1401 | 3564 | 4545 | 0.7840 | 0.7329 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 1 | H05 | 72 | hr | 1401 | 2763 | 3978 | 0.6945 | 0.5698 |