LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1209 1439 3980 0.3616 0.1064
MCF7 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1209 1442 4252 0.3391 0.1018
MCF7 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1209 1397 4376 0.3192 0.0808
MCF7 Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 1209 1335 3980 0.3354 0.0591
MCF7 Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 1209 1196 4252 0.2812 -0.0062
MCF7 Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 1209 1313 4376 0.3000 0.0452
MCF7 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1209 3795 3823 0.9927 0.9912
MCF7 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1209 3877 4093 0.9470 0.9391
MCF7 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1209 3991 4121 0.9684 0.9640
MCF7 Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 1209 3753 3823 0.9817 0.9779
MCF7 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 1209 4015 4093 0.9807 0.9780
MCF7 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 1209 4066 4121 0.9866 0.9848
MCF7 Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 1209 3675 3823 0.9613 0.9530
MCF7 Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 1209 4220 4093 1.0308 1.0348
MCF7 Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 1209 4271 4121 1.0363 1.0408
MCF7 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 1209 4098 3823 1.0719 1.0855
MCF7 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 1209 3869 4093 0.9451 0.9368
MCF7 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 1209 4023 4121 0.9762 0.9729
MCF7 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 1209 3594 3823 0.9401 0.9270
MCF7 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 1209 3880 4093 0.9478 0.9399
MCF7 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 1209 4046 4121 0.9818 0.9793
MCF7 Imatinib
10
uM
LJP6
 1
N13
 72
hr
 1209 3363 3823 0.8797 0.8514
MCF7 Imatinib
10
uM
LJP6
 2
N13
 72
hr
 1209 3571 4093 0.8723 0.8505
MCF7 Imatinib
10
uM
LJP6
 3
N13
 72
hr
 1209 3657 4121 0.8874 0.8693
MCF7 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1209 1874 3823 0.4902 0.3018