LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 1 | L19 | 72 | hr | 1401 | 1359 | 3978 | 0.3416 | -0.0203 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 2 | L19 | 72 | hr | 1401 | 1449 | 4213 | 0.3439 | 0.0212 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 3 | L19 | 72 | hr | 1401 | 1406 | 4545 | 0.3093 | 0.0019 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 1401 | 4700 | 4139 | 1.1355 | 1.1695 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 2 | M12 | 72 | hr | 1401 | 4689 | 4095 | 1.1450 | 1.1829 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 3 | M12 | 72 | hr | 1401 | 4478 | 4272 | 1.0481 | 1.0593 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 1 | M11 | 72 | hr | 1401 | 4430 | 4139 | 1.0703 | 1.0889 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 2 | M11 | 72 | hr | 1401 | 4200 | 4095 | 1.0256 | 1.0329 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 3 | M11 | 72 | hr | 1401 | 4321 | 4272 | 1.0114 | 1.0141 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 1 | M10 | 72 | hr | 1401 | 4556 | 4139 | 1.1007 | 1.1267 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 2 | M10 | 72 | hr | 1401 | 4038 | 4095 | 0.9860 | 0.9819 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 3 | M10 | 72 | hr | 1401 | 4437 | 4272 | 1.0385 | 1.0476 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 1401 | 4023 | 4139 | 0.9720 | 0.9639 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 1401 | 3897 | 4095 | 0.9516 | 0.9368 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 1401 | 4222 | 4272 | 0.9882 | 0.9853 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 1 | M08 | 72 | hr | 1401 | 4546 | 4139 | 1.0983 | 1.1237 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 2 | M08 | 72 | hr | 1401 | 4035 | 4095 | 0.9853 | 0.9809 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 3 | M08 | 72 | hr | 1401 | 4516 | 4272 | 1.0570 | 1.0702 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 1 | M07 | 72 | hr | 1401 | 4528 | 4139 | 1.0940 | 1.1184 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 2 | M07 | 72 | hr | 1401 | 4105 | 4095 | 1.0024 | 1.0030 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 3 | M07 | 72 | hr | 1401 | 3944 | 4272 | 0.9231 | 0.9030 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 1 | F06 | 72 | hr | 1401 | 3216 | 4139 | 0.7770 | 0.7017 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 2 | F06 | 72 | hr | 1401 | 2906 | 4095 | 0.7096 | 0.6022 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 3 | F06 | 72 | hr | 1401 | 3111 | 4272 | 0.7282 | 0.6419 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 1 | F05 | 72 | hr | 1401 | 2771 | 4139 | 0.6695 | 0.5470 |