LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Momelotinib | 10 | uM | LJP5 | 3 | P07 | 72 | hr | 1389 | 1779 | 6038 | 0.2946 | 0.1238 |
| MCF7 | Fedratinib | 0.04 | uM | LJP5 | 1 | L06 | 72 | hr | 1389 | 6057 | 5772 | 1.0493 | 1.0474 |
| MCF7 | Fedratinib | 0.04 | uM | LJP5 | 3 | L06 | 72 | hr | 1389 | 6061 | 6038 | 1.0037 | 1.0035 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 1 | L05 | 72 | hr | 1389 | 5977 | 5772 | 1.0354 | 1.0342 |
| MCF7 | Fedratinib | 0.12 | uM | LJP5 | 3 | L05 | 72 | hr | 1389 | 6081 | 6038 | 1.0070 | 1.0066 |
| MCF7 | Fedratinib | 0.37 | uM | LJP5 | 1 | L04 | 72 | hr | 1389 | 5459 | 5772 | 0.9457 | 0.9464 |
| MCF7 | Fedratinib | 0.37 | uM | LJP5 | 3 | L04 | 72 | hr | 1389 | 5462 | 6038 | 0.9045 | 0.9076 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 1 | L03 | 72 | hr | 1389 | 4929 | 5772 | 0.8539 | 0.8520 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 3 | L03 | 72 | hr | 1389 | 4529 | 6038 | 0.7500 | 0.7462 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 1 | L02 | 72 | hr | 1389 | 1921 | 5772 | 0.3328 | 0.1709 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 3 | L02 | 72 | hr | 1389 | 2323 | 6038 | 0.3847 | 0.2745 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 1 | L01 | 72 | hr | 1389 | 779 | 5772 | 0.1350 | -0.2453 |
| MCF7 | Fedratinib | 10 | uM | LJP5 | 3 | L01 | 72 | hr | 1389 | 945 | 6038 | 0.1565 | -0.1661 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 1 | P24 | 72 | hr | 1389 | 2625 | 5772 | 0.4547 | 0.3630 |
| MCF7 | Trametinib | 0.04 | uM | LJP5 | 3 | P24 | 72 | hr | 1389 | 2744 | 6038 | 0.4544 | 0.3787 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 1 | P23 | 72 | hr | 1389 | 2350 | 5772 | 0.4071 | 0.2916 |
| MCF7 | Trametinib | 0.12 | uM | LJP5 | 3 | P23 | 72 | hr | 1389 | 3080 | 6038 | 0.5101 | 0.4559 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 1 | P22 | 72 | hr | 1389 | 2626 | 5772 | 0.4549 | 0.3633 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 3 | P22 | 72 | hr | 1389 | 2753 | 6038 | 0.4559 | 0.3808 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 1 | P21 | 72 | hr | 1389 | 2499 | 5772 | 0.4329 | 0.3308 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 3 | P21 | 72 | hr | 1389 | 2734 | 6038 | 0.4528 | 0.3763 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 1 | P20 | 72 | hr | 1389 | 2885 | 5772 | 0.4998 | 0.4271 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 3 | P20 | 72 | hr | 1389 | 2973 | 6038 | 0.4923 | 0.4318 |
| MCF7 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 1389 | 2558 | 5772 | 0.4431 | 0.3460 |
| MCF7 | Trametinib | 10 | uM | LJP5 | 3 | P19 | 72 | hr | 1389 | 3196 | 6038 | 0.5293 | 0.4815 |