LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 1694 10362 11042 0.9384 0.9535
MCF 10A GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 1694 9859 11099 0.8882 0.9145
MCF 10A GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 1694 10385 11168 0.9299 0.9473
MCF 10A GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 1694 7299 11042 0.6610 0.7161
MCF 10A GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 1694 7217 11099 0.6502 0.7064
MCF 10A GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 1694 7174 11168 0.6424 0.6997
MCF 10A GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 1694 4130 11042 0.3740 0.3903
MCF 10A GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 1694 4391 11099 0.3956 0.4207
MCF 10A GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 1694 4108 11168 0.3678 0.3848
MCF 10A GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 1694 2632 11042 0.2384 0.1769
MCF 10A GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 1694 2696 11099 0.2429 0.1869
MCF 10A GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 1694 2251 11168 0.2016 0.1101
MCF 10A GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 1694 2619 11042 0.2372 0.1748
MCF 10A GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 1694 2445 11099 0.2203 0.1448
MCF 10A GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 1694 2099 11168 0.1879 0.0819
MCF 10A GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 1694 2151 11042 0.1948 0.0923
MCF 10A GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 1694 1934 11099 0.1742 0.0500
MCF 10A GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 1694 2271 11168 0.2033 0.1137
MCF 10A Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 1694 3052 11220 0.2720 0.2408
MCF 10A Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 1694 3252 11309 0.2876 0.2688
MCF 10A Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 1694 3286 11121 0.2955 0.2764
MCF 10A Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 1694 3330 11042 0.3016 0.2839
MCF 10A Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 1694 3018 11099 0.2719 0.2373
MCF 10A Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 1694 3370 11168 0.3018 0.2876
MCF 10A Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 1694 1610 11220 0.1435 -0.0185